What are the management options for swelling and watering after glaucoma surgery?

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Last updated: October 7, 2025View editorial policy

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Management of Swelling and Watering After Glaucoma Surgery

Topical corticosteroids should be prescribed as the primary treatment for managing swelling and watering after glaucoma surgery, with frequent follow-up evaluations to monitor response and adjust treatment as needed. 1

Initial Post-Operative Management

  • Perform a follow-up evaluation on the first postoperative day and at least once during the first 1-2 weeks to evaluate visual acuity, intraocular pressure (IOP), and status of the anterior segment 1
  • Prescribe topical corticosteroids in the postoperative period to control inflammation 1
  • Schedule more frequent follow-up visits for patients with postoperative complications such as increased inflammation, flat or shallow anterior chamber, or early bleb failure 1

Management of Specific Complications

For Bleb-Related Issues:

  • If evidence of bleb failure develops (indicated by rising IOP and flattening bleb), undertake additional treatments to improve aqueous flow, including: 1
    • Injection of antifibrotic agents
    • Bleb massage
    • Suture adjustment, release, or lysis
    • Bleb needling

For Inflammation and Swelling:

  • Continue topical corticosteroids with appropriate frequency based on the severity of inflammation 1
  • Monitor for steroid-related complications such as IOP elevation 1
  • Consider non-steroidal anti-inflammatory drugs (NSAIDs) as adjunctive therapy in cases of persistent inflammation 1

For Excessive Watering (Epiphora):

  • Evaluate for bleb leak if watering is accompanied by low IOP 1
  • Repair bleb leak if identified 1
  • Consider temporary patching or bandage contact lens for small leaks 1

Follow-up Protocol

  • In the absence of complications, perform additional postoperative visits during a 3-month period to evaluate visual acuity, IOP, and status of the anterior segment 1
  • For patients with persistent swelling or watering, increase visit frequency to monitor response to treatment 1
  • Examine for macular thickening which may occur as a physiological reaction to sudden IOP reduction after glaucoma surgery 2

Patient Education

  • Explain that filtration surgery places the eye at risk for endophthalmitis for the duration of the patient's life 1
  • Instruct patients to notify their ophthalmologist immediately if they experience symptoms of pain, decreased vision, redness, or discharge 1
  • Educate patients about proper administration of prescribed medications and importance of adherence to the treatment regimen 3

Special Considerations

  • For patients with persistent inflammation despite standard therapy, consider evaluation for underlying causes such as retained lens material or uveitis 4
  • Monitor for macular changes, as studies have shown a slight subclinical increase in macular thickness after uncomplicated trabeculectomy 2
  • Be aware that sudden reduction in IOP after glaucoma surgery can alter the relationship between capillary pressure and interstitial fluid pressure, potentially contributing to macular thickening 2

Common Pitfalls and Caveats

  • Avoid premature discontinuation of topical corticosteroids, as this may lead to rebound inflammation 1
  • Do not ignore persistent watering, as it may indicate a bleb leak which can increase the risk of endophthalmitis 1
  • Be vigilant for signs of infection, which requires immediate and aggressive treatment to prevent vision loss 1, 4
  • Recognize that excessive manipulation of the bleb during the early postoperative period may increase the risk of complications 5

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Macular thickness after glaucoma filtration surgery.

Collegium antropologicum, 2013

Research

Updates on the Diagnosis and Management of Glaucoma.

Mayo Clinic proceedings. Innovations, quality & outcomes, 2022

Research

Management of complications in glaucoma surgery.

Indian journal of ophthalmology, 2011

Research

Current techniques in wound healing modulation in glaucoma surgery.

Current opinion in ophthalmology, 1996

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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