Signs and Symptoms of Cervical Stenosis
Cervical spinal stenosis typically presents with a combination of neck pain, radiating pain in the arms, weakness, and neurological deficits that can progress to significant morbidity if left untreated.
Common Clinical Presentations
Neck pain with radiating pain in one arm - The most common presentation is neck pain combined with pain in one arm accompanied by varying degrees of sensory or motor function loss in the affected nerve-root distribution 1
Radiculopathy - Manifests as radiating pain, numbness, or tingling in the arms due to nerve root compression 2
Weakness - May affect upper and/or lower extremities due to spinal cord compression 2
Myelopathy signs - Include:
Neurogenic claudication - Pain with walking or standing that improves with rest 2
Worsening symptoms with neck extension - Pain may intensify with certain neck positions or prolonged static postures 2
Diagnostic Indicators
Cord signal changes on MRI - T2-weighted hyperintensity indicates myelopathy 2
Residual spinal canal diameter - Patients with canal diameter <10mm are at significantly higher risk of neurologic deterioration after even minor trauma compared to those with canal diameter ≥10mm 3
Proprioception deficits - The degree of cervical stenosis significantly affects cervical proprioception and range of motion, with more severe stenosis associated with greater joint position errors 4
Risk Factors for Progression
Ossification of the Posterior Longitudinal Ligament (OPLL) - Predisposes patients to progressive narrowing of the spinal canal and/or abutment of the spinal cord, typically presenting in the fifth or sixth decade of life with a 2:1 male-to-female ratio 1
Symptomatic radiculopathy - The presence of clinically symptomatic radiculopathy in patients with cervical stenosis but without myelopathy is considered a significant predictor of progression to myelopathy 5
Cervical cord hyperintensity on MRI - Associated with late myelopathy development (mean 44-month follow-up) 5
Prolonged somatosensory and motor-evoked potentials - Significant independent predictors of myelopathy development 5
Natural History and Progression
Variable disease course - Many patients experience slow, stepwise decline with long periods of quiescence and interim improvement 2
Risk of sudden deterioration - Even minor trauma to the neck can cause irreversible changes in the spinal cord if there is marked stenosis of the cervical spinal canal 3
Untreated severe compression - Carries a mortality rate of 16% in cases of cervicomedullary compression 2
Potential irreversible damage - Long periods of severe stenosis can lead to demyelination of white matter and potentially irreversible neurological deficits 2
Special Considerations
Asymptomatic radiographic stenosis - Does not necessarily require intervention, as the relationship between radiographic findings and symptoms is not always straightforward 2
Screening recommendation - It may be beneficial to check lateral radiographs of the cervical spine as a screening tool for early detection of cervical spinal stenosis, especially in Asian people older than 40 years 3
Coexisting stenosis - Cervical stenosis may coexist with lumbar stenosis, requiring careful evaluation of symptoms to determine the primary source of neurological deficits 6