Does wine increase cholesterol levels?

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Last updated: March 22, 2025View editorial policy

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From the Guidelines

Wine consumption, in moderation, is not likely to significantly increase cholesterol levels and may even have beneficial effects on HDL cholesterol, but excessive consumption can raise triglyceride levels and contribute to other health problems. The relationship between wine consumption and cholesterol levels is complex, with moderate consumption potentially increasing HDL (good) cholesterol and reducing LDL (bad) cholesterol oxidation due to antioxidants like resveratrol 1. However, excessive alcohol consumption from any source, including wine, can lead to increased triglyceride levels and contribute to other health issues, such as hypertriglyceridemia, hypertension, and liver damage 1.

The American Heart Association recommends moderate alcohol consumption, defined as up to one glass daily for women and up to two glasses daily for men, but notes that these potential benefits do not justify starting to drink wine if one does not already consume it, as the overall health risks of alcohol may outweigh the cholesterol benefits 1. Other lifestyle factors, such as regular exercise, a heart-healthy diet, maintaining a healthy weight, and not smoking, have more significant and proven effects on improving cholesterol levels.

Key points to consider:

  • Moderate wine consumption may have beneficial effects on HDL cholesterol
  • Excessive alcohol consumption can raise triglyceride levels and contribute to other health problems
  • The American Heart Association recommends moderate alcohol consumption
  • Other lifestyle factors have more significant effects on improving cholesterol levels
  • If you have existing cholesterol problems, consult with your healthcare provider before making decisions about alcohol consumption 1.

From the Research

Wine Consumption and Cholesterol Levels

  • The relationship between wine consumption and cholesterol levels is not directly addressed in the provided studies 2, 3, 4, 5, 6.
  • However, some studies suggest that moderate wine consumption may have beneficial effects on cardiovascular health, which could be related to cholesterol levels 2, 3, 6.
  • A study on the effects of moderate wine consumption on subjects with cardiovascular risk factors found changes in urinary metabolomic markers, including those related to gut microbiota and endogenous modifications 5.
  • Another study discussed the benefits and risks of moderate alcohol consumption on cardiovascular disease, highlighting the complexities of the relationship between alcohol intake and cardiovascular health 6.
  • A study on low high-density lipoprotein cholesterol and cardiovascular disease discussed the importance of statin therapy in reducing cardiovascular risk, but did not specifically address the effect of wine consumption on cholesterol levels 4.

Key Findings

  • Moderate wine consumption may be associated with reduced risk of cardiovascular disease mortality 3.
  • The relationship between wine consumption and cholesterol levels is not clearly established in the provided studies.
  • Further research is needed to fully understand the effects of wine consumption on cardiovascular health and cholesterol levels 3, 6.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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