What causes pruritus after ultraviolet (UV) radiation-induced erythema, also known as sunburn?

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From the Research

Your skin itches after a sunburn because of the inflammatory response triggered by UV radiation damage, which is supported by the most recent study available, although not directly related to the question, the general concept of UV radiation damage is consistent across studies 1. When your skin gets sunburned, the UV rays damage skin cells, causing them to release chemicals that activate your immune system. This immune response includes increased blood flow to the area (causing redness) and the release of substances like histamines and cytokines, which stimulate nerve endings and cause itching. The following key points are relevant to understanding the cause of pruritus after sunburn:

  • UV radiation damage to skin cells triggers an inflammatory response
  • The immune response includes the release of substances like histamines and cytokines, which stimulate nerve endings and cause itching
  • As the skin begins to heal, the damaged top layer dries out and starts to peel, creating physical irritation that contributes to the itchy sensation Although the provided studies do not directly address the question of what causes pruritus after sunburn, the general concept of UV radiation damage and its effects on the skin is consistent across studies 2, 3, 4, 5. To relieve sunburn itch, consider the following treatments:
  • Take cool baths with colloidal oatmeal
  • Apply aloe vera gel or calamine lotion to the affected areas
  • Use over-the-counter hydrocortisone cream (0.5-1%) up to twice daily for a few days
  • Take oral antihistamines like diphenhydramine (Benadryl) 25-50mg every 4-6 hours as needed Staying hydrated and moisturizing regularly with fragrance-free lotions will help maintain skin moisture as it heals. Avoid scratching the area as this can lead to infection and delay healing.

References

Research

Natural components in sunscreens: Topical formulations with sun protection factor (SPF).

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021

Research

Itching and the atopic skin.

The Journal of allergy and clinical immunology, 1999

Research

Sunscreens prevent sunburn cell formation in human skin.

The Journal of investigative dermatology, 1980

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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