What is the recommended treatment for a sty (hordeolum)?

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Treatment of Stye (Hordeolum)

Warm compresses applied to the affected eyelid for 10-15 minutes several times daily is the recommended first-line treatment for a stye (hordeolum). 1, 2, 3

First-Line Management

  • Apply warm compresses to the affected eyelid for 10-15 minutes, 3-4 times daily to promote drainage of the infected gland 1, 2
  • Maintain good eyelid hygiene with gentle lid scrubs to keep the area clean 4
  • Avoid touching or squeezing the stye to prevent spreading infection 4
  • Avoid wearing contact lenses and eye makeup until the stye resolves 3

When to Consider Antibiotics

  • Topical antibiotic ointments (such as erythromycin or bacitracin) may be considered if:

    • The stye is large or particularly painful 3
    • There is significant surrounding erythema or cellulitis 4
    • The infection appears to be spreading beyond the immediate area 4
  • Oral antibiotics should be reserved for cases with:

    • Significant surrounding cellulitis 4
    • Systemic symptoms (fever, malaise) 4
    • Failed response to topical therapy 4

Antibiotic Options (When Indicated)

  • For topical use: mupirocin 2% ointment applied to the affected eyelid margin 4
  • For oral therapy (if needed for more severe cases):
    • Clindamycin (300-450 mg orally three times daily) 4
    • Trimethoprim-sulfamethoxazole (1-2 DS tablets twice daily) 4
    • Doxycycline (100 mg twice daily) - not for children under 8 years 4

Special Considerations

For Children

  • Warm compresses remain the first-line treatment 1, 2
  • Mupirocin 2% topical ointment can be used for minor infections 4
  • Avoid tetracyclines in children under 8 years of age 4
  • For more severe cases requiring systemic therapy, clindamycin at 10-13 mg/kg/dose IV every 6-8 hours (to administer 40 mg/kg/day) is an option 4

For Recurrent Styes

  • Continue regular warm compresses and lid hygiene 4
  • Consider decolonization strategies:
    • Nasal mupirocin twice daily for 5-10 days 4
    • Topical body decolonization with chlorhexidine for 5-14 days 4
    • Dilute bleach baths (1 teaspoon per gallon of water for 15 minutes twice weekly) 4

When to Refer to an Ophthalmologist

  • No improvement after 48-72 hours of appropriate treatment 3
  • Visual changes or severe pain 3
  • Recurrent styes despite appropriate treatment 4
  • Progression to a chalazion (painless, firm nodule) 2
  • Spread of infection beyond the eyelid 4

Evidence Limitations

It's important to note that despite the widespread recommendation of warm compresses as first-line therapy, Cochrane systematic reviews found no randomized controlled trials specifically evaluating non-surgical interventions for internal hordeolum 1, 2. Treatment recommendations are largely based on clinical experience and expert opinion rather than high-quality evidence.

References

Research

Interventions for acute internal hordeolum.

The Cochrane database of systematic reviews, 2013

Research

Non-surgical interventions for acute internal hordeolum.

The Cochrane database of systematic reviews, 2017

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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