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Differential Diagnosis for Urethral Burning after Ejaculation

  • Single most likely diagnosis
    • Prostatitis: This condition, which involves inflammation of the prostate gland, is a common cause of urethral burning after ejaculation. The prostate surrounds the urethra, and inflammation can cause irritation and burning sensations, especially during or after ejaculation.
  • Other Likely diagnoses
    • Urethritis: Inflammation of the urethra, often due to infection, can cause burning sensations during or after ejaculation. This condition can be caused by bacterial, viral, or fungal infections.
    • Epididymitis: Inflammation of the epididymis, a tube at the back of the testicle that stores and carries sperm, can cause pain and burning sensations, including after ejaculation.
    • Urinary Tract Infection (UTI): While more common in women, men can also experience UTIs, which can cause burning sensations during urination and potentially after ejaculation if the infection involves the urethra.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Gonorrhea or Chlamydia: These sexually transmitted infections (STIs) can cause urethritis and epididymitis, leading to symptoms like urethral burning after ejaculation. Early diagnosis and treatment are crucial to prevent long-term complications, such as infertility.
    • Tuberculosis (TB) of the Genitourinary Tract: Although rare, TB can affect the genitourinary system and cause a variety of symptoms, including urethral burning. Missing this diagnosis could lead to severe consequences due to the potential for TB to spread to other parts of the body.
  • Rare diagnoses
    • Reiter's Syndrome (Reactive Arthritis): A form of arthritis that occurs as a reaction to a bacterial infection in another part of the body, often the intestines or the urethra. It can cause urethritis, leading to burning sensations.
    • Interstitial Cystitis: A condition causing bladder pressure, bladder pain, and sometimes pelvic pain. The symptoms can worsen with ejaculation in some cases, leading to urethral burning sensations.
    • Sjögren's Syndrome: An autoimmune disorder that can cause inflammation in various parts of the body, including the genitourinary system, potentially leading to symptoms like urethral burning.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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