Differential Diagnosis for AGEP and Pustular Psoriasis
Single Most Likely Diagnosis
- Pustular Psoriasis: This is the most likely diagnosis due to the presence of pustules, which are a hallmark of pustular psoriasis. The condition is characterized by the sudden appearance of pustules on the skin, often accompanied by systemic symptoms such as fever and malaise.
Other Likely Diagnoses
- Acute Generalized Exanthematous Pustulosis (AGEP): AGEP is a skin condition characterized by the sudden onset of numerous small pustules, often accompanied by fever and leukocytosis. It is usually triggered by medications or infections.
- Impetigo: Impetigo is a bacterial skin infection that can cause pustules, especially in children. It is highly contagious and can be spread through direct contact with the infected area.
- Folliculitis: Folliculitis is an inflammation of the hair follicles, which can cause pustules. It can be caused by bacterial or fungal infections.
Do Not Miss Diagnoses
- Toxic Epidermal Necrolysis (TEN): TEN is a life-threatening skin condition that can cause widespread skin necrosis and detachment. It is often triggered by medications and can be fatal if not recognized and treated promptly.
- Staphylococcal Scalded Skin Syndrome (SSSS): SSSS is a bacterial infection that can cause widespread skin lesions and pustules, especially in children. It is caused by staphylococcal toxins and can be life-threatening if not treated promptly.
- Septicemia: Septicemia is a life-threatening condition that occurs when bacteria enter the bloodstream and cause a systemic infection. It can cause pustules and other skin lesions, and can be fatal if not recognized and treated promptly.
Rare Diagnoses
- Subcorneal Pustular Dermatosis: This is a rare skin condition characterized by the presence of pustules in the subcorneal layer of the skin. It is often associated with systemic diseases such as rheumatoid arthritis.
- IgA Pemphigus: IgA pemphigus is a rare autoimmune skin disease that can cause pustules and blistering lesions. It is often associated with other autoimmune diseases.
- Pustular Dermatosis of Pregnancy: This is a rare skin condition that occurs during pregnancy, characterized by the presence of pustules and other skin lesions. It is often associated with other pregnancy-related complications.