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Last updated: October 8, 2025View editorial policy

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Differential Diagnosis for Lower Back and Left Abdominal Pain

Single Most Likely Diagnosis

  • Musculoskeletal strain: Given the presentation of lower back pain and left abdominal pain, a musculoskeletal strain is a common and likely diagnosis. This could be due to overuse, poor posture, or a sudden injury, leading to strain in the muscles or ligaments of the back and abdominal wall.

Other Likely Diagnoses

  • Nephrolithiasis (Kidney Stones): Pain in the lower back that radiates to the abdomen, especially if it's severe and colicky, could indicate a kidney stone. The pain is often accompanied by nausea, vomiting, and sometimes blood in the urine.
  • Diverticulitis: Inflammation of a diverticulum in the colon can cause lower abdominal pain, which may radiate to the back. It's more common in older adults and can be accompanied by fever, nausea, and changes in bowel habits.
  • Pyelonephritis: An infection of the kidney can cause flank pain, which may radiate to the abdomen, along with symptoms like fever, chills, and dysuria.

Do Not Miss Diagnoses

  • Appendicitis: Although appendicitis typically presents with right lower quadrant pain, it can occasionally present with left lower quadrant pain if the appendix is retrocecal or if there's an anomaly in its location. Missing this diagnosis can lead to perforation and severe complications.
  • Ectopic Pregnancy: In women of childbearing age, ectopic pregnancy is a critical diagnosis to consider, especially if there's a history of missed periods or positive pregnancy test. It can present with abdominal pain and may radiate to the back.
  • Aortic Aneurysm or Dissection: A sudden, severe pain in the back or abdomen could indicate an aortic aneurysm or dissection, which is a medical emergency requiring immediate intervention.

Rare Diagnoses

  • Pancreatitis: Inflammation of the pancreas can cause severe abdominal pain that radiates to the back. It's often associated with gallstones or excessive alcohol use.
  • Pheochromocytoma: A rare tumor of the adrenal gland can cause episodic hypertension, sweating, palpitations, and abdominal or back pain.
  • Lead Poisoning: Can cause abdominal pain and constipation, though it's less common and usually associated with exposure history.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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