Treatment Options for Hemiparetic Spasms
Botulinum toxin injections are the first-line treatment for hemiparetic spasms related to spasticity, particularly when targeting specific muscle groups like the subscapularis and pectoralis muscles in the upper extremity. 1
Initial Assessment and Non-Pharmacological Approaches
- Assessment of hemiparetic spasms should include evaluation of tone, strength, changes in soft tissue length, joint alignment, pain levels, and orthopedic changes 1
- Active, active-assisted, or passive range of motion exercises should be implemented early to prevent contractures and complex regional pain syndrome (CRPS) 1
- Positioning, stretching, and mobilization techniques should focus on increasing external rotation and abduction for upper extremity spasticity 1
- Functional dynamic orthoses may facilitate repetitive task-specific training for affected limbs 1
Pharmacological Management
Oral Medications
- If no contraindications exist, analgesics such as acetaminophen or ibuprofen can be used for pain relief associated with spasticity 1
- Oral antispasmodic medications can be considered in this order:
- Tizanidine (starting at 300 mg at bedtime, up to 2400 mg daily in divided doses) - particularly effective for chronic stroke patients 1, 2
- Dantrolene for spasticity resulting in pain, poor skin hygiene, or decreased function 1
- Oral baclofen (though efficacy in stroke has not been established according to FDA labeling) 1, 3
- Avoid benzodiazepines during stroke recovery due to potential negative effects on recovery and sedation side effects 1
Injectable Treatments
- Botulinum toxin injections into specific muscles (such as subscapularis and pectoralis) are effective for treating spasticity-related pain and improving range of motion 1
- Subacromial corticosteroid injections can be used when pain is related to injury or inflammation of the subacromial region in the hemiplegic shoulder 1
Advanced Interventions
- For severe, intractable spasticity unresponsive to other treatments, intrathecal baclofen (ITB) may be considered, but with caution 4
- ITB must be used carefully in stroke patients as it may weaken the paretic side and suppress antigravity patterns used for ambulation 5
Management of Associated Conditions
Hemiplegic Shoulder Pain
- Active range of motion should be increased gradually while restoring alignment and strengthening weak muscles in the shoulder girdle 1
- Repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) may be considered as adjuncts to upper extremity therapy 1
Complex Regional Pain Syndrome (CRPS)
- For CRPS associated with hemiparesis, an early course of oral corticosteroids (30-50 mg daily for 3-5 days, with tapering doses over 1-2 weeks) can reduce swelling and pain 1
- Diagnosis should be based on clinical findings including pain and tenderness of joints, edema, trophic skin changes, hyperesthesia, and limited range of motion 1
Rehabilitation Approaches
- Balance training should be offered to patients with balance disorders post-stroke 1
- Effective interventions include trunk training, task-oriented intervention, force platform biofeedback, and structured progressive exercise programs 1
- For lower limb spasticity, transcutaneous electrical nerve stimulation (TENS) may be as effective as or more effective than oral baclofen with fewer side effects 6
Important Considerations and Pitfalls
- Functional assessment is critical before treatment, as reducing spasticity may sometimes worsen function if the patient relies on spasticity for stability or movement patterns 5
- Spasticity management should aim to decrease tone without reducing muscle strength needed for functional activities 1
- Regular reassessment is essential to determine if changes to treatment are required or if equipment can be discontinued as the patient improves 1
- Adaptive devices should be evaluated on an individual basis and may be necessary for safety and function 1