Differential Diagnosis for Uvula Swollen and Sore Throat in 69 M with hx of CAD
- Single most likely diagnosis
- Acute Pharyngitis (likely viral or bacterial): This is the most common cause of a sore throat and swollen uvula in adults. The patient's age and history of CAD do not specifically point towards a less common diagnosis, making this the most likely initial consideration.
- Other Likely diagnoses
- Tonsillitis: Inflammation of the tonsils can cause a sore throat and may also involve the uvula, especially if the infection spreads.
- Gastroesophageal Reflux Disease (GERD): GERD can cause irritation of the throat, leading to soreness and swelling, including the uvula, due to the reflux of stomach acid.
- Allergic Reaction: An allergic reaction could cause swelling and soreness in the throat, including the uvula, though this would typically be accompanied by other symptoms such as rash, itching, or difficulty breathing.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Epiglottitis: Although less common, epiglottitis is a life-threatening condition that can cause severe swelling of the epiglottis and surrounding structures, including the uvula, leading to airway obstruction. It's crucial to consider this diagnosis, especially in adults with a sore throat and uvular swelling.
- Angioedema: Part of an allergic reaction, angioedema can cause rapid swelling of the face, lips, tongue, and throat, which can lead to airway obstruction. Given the patient's history of CAD, any condition that could potentially compromise the airway is critical to identify promptly.
- Peritonsillar Abscess: A complication of tonsillitis, a peritonsillar abscess can cause severe throat pain, difficulty swallowing, and fever. While not directly involving the uvula, it's a serious condition that requires prompt diagnosis and treatment.
- Rare diagnoses
- Infectious Mononucleosis: Caused by the Epstein-Barr virus, this condition can lead to sore throat, fever, and swollen lymph nodes, but it's more common in younger populations.
- Lemierre's Syndrome: A rare condition characterized by a bacterial infection of the throat, leading to complications such as thrombophlebitis of the internal jugular vein. It's a rare but serious condition that could present with sore throat and uvular swelling among other symptoms.
- Malignancy: Though rare, cancers of the throat or uvula could present with soreness and swelling. Given the patient's age, this is a consideration, especially if the symptoms are persistent or worsening over time.