Does perineural steroid injection help with acute pain, such as rib fractures, or is it only effective for chronic neuropathic pain?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 9, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Perineural Steroid Injections for Acute Pain Management in Rib Fractures

Perineural steroid injections are effective for both acute pain management, including rib fractures, and not just for chronic neuropathic pain. 1

Effectiveness of Regional Anesthetic Techniques for Rib Fractures

  • Regional anesthetic techniques, including perineural injections, are highly effective for managing acute pain associated with traumatic rib fractures 2
  • Strong evidence confirms that peripheral nerve blocks (PNBs) in managing acute pain from traumatic fractures effectively decrease opioid use, pain, and hospital length of stay 2
  • Thoracic epidural steroid injections have been successfully used specifically for rib fracture pain management, representing an effective interventional approach 1

Mechanism and Benefits

  • Perineural injections target both nociceptive pain from osseous injury and neuropathic pain from nerve insult in rib fractures 1
  • These techniques allow localized delivery of analgesia to specific painful areas and augment multimodal analgesic regimens 2
  • Regional anesthesia techniques have become increasingly promising alternatives to systemic opioids due to their superior efficacy and fewer adverse effects 3

Comparison to Other Analgesic Approaches

  • Peripheral nerve blocks showed superior analgesic effect compared to opioids during movement, resulting in lower analgesic consumption and longer time before requesting additional pain relief 2
  • PNBs reduced pain on movement within 30 minutes after block placement, while also reducing risk of acute confusional state, chest infection, and improving time to first mobilization 2
  • When compared to epidural analgesia, perineural techniques may be safer alternatives with fewer contraindications, particularly in anticoagulated patients or those with vertebral fractures 4

Specific Techniques for Rib Fractures

  • Thoracic epidural steroid injections can be used specifically for rib fracture pain management 1
  • Newer myofascial plane blocks such as erector spinae plane (ESP) block and serratus anterior plane (SAP) block have emerged as effective alternatives with minimal side effects 4
  • These blocks provide excellent analgesia with fewer contraindications than traditional epidural approaches 3, 4

Implementation in Clinical Practice

  • For patients with rib fractures, a multimodal approach incorporating perineural injections alongside scheduled acetaminophen provides optimal pain control 5, 6
  • Regional anesthetic techniques should be considered early in the treatment algorithm, especially for high-risk patients such as the elderly 5, 6
  • Intravenous lidocaine may be an alternative when perineural injections are not feasible, showing similar pain reduction to epidural analgesia 7

Practical Considerations and Limitations

  • Careful evaluation of anticoagulation status is essential before performing neuraxial or plexus blocks to avoid bleeding complications 6
  • Timing is important - early implementation of regional anesthetic techniques provides better outcomes than delayed intervention 2, 5
  • Some techniques like paravertebral blocks may have failure rates up to 10% and potential complications in trauma settings 3

Patient Selection

  • Elderly patients (>60 years) with rib fractures benefit significantly from regional anesthetic techniques due to their higher risk of complications 2, 6
  • Patients with multiple rib fractures or flail chest are ideal candidates for perineural injections to improve respiratory mechanics and prevent pulmonary complications 5
  • Patients with contraindications to opioids or NSAIDs particularly benefit from regional anesthetic approaches 6

In conclusion, perineural steroid injections are effective for both acute pain management in rib fractures and chronic neuropathic pain, with evidence supporting their use as part of a comprehensive analgesic strategy to improve outcomes and reduce complications.

References

Research

Thoracic epidural steroid injection for rib fracture pain.

Pain practice : the official journal of World Institute of Pain, 2013

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

An update on regional analgesia for rib fractures.

Current opinion in anaesthesiology, 2018

Guideline

Management of Rib Fractures

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Analgesic Management for Elderly Patients with Rib Fractures

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.