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Last updated: October 9, 2025View editorial policy

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Differential Diagnosis for Burning Tongue

  • Single most likely diagnosis
    • Burning Mouth Syndrome (BMS): This condition is characterized by a burning sensation in the tongue and other areas of the mouth without any visible signs of oral disease. It's often related to menopause, dry mouth, or psychological factors, making it a common diagnosis for burning tongue complaints.
  • Other Likely diagnoses
    • Oral candidiasis (thrush): A fungal infection that can cause burning sensations, especially in immunocompromised patients or those with poor oral hygiene.
    • Geographic tongue: A condition where areas of the tongue become denuded of their papillae, leading to discomfort and a burning sensation.
    • Nutritional deficiencies (e.g., vitamin B12, iron, or zinc deficiency): These deficiencies can cause oral symptoms, including a burning sensation in the tongue.
    • Dry mouth (xerostomia): Reduced saliva production can lead to a burning sensation in the mouth and tongue.
  • Do Not Miss diagnoses
    • Oral cancer: Although rare, oral cancer can present with a burning sensation in the tongue. Early detection is crucial for effective treatment.
    • Lichen planus: An autoimmune condition that can affect the mucous membranes inside the mouth, leading to a burning sensation and potentially increasing the risk of oral cancer.
    • Diabetes: Uncontrolled diabetes can lead to oral symptoms, including a burning tongue, due to high blood sugar levels affecting nerve function.
  • Rare diagnoses
    • Sjögren's syndrome: An autoimmune disorder that primarily affects the glands that produce tears and saliva, leading to dry mouth and potentially a burning tongue.
    • Pernicious anemia: A condition where the body can't make enough healthy red blood cells due to a lack of vitamin B12, which can cause a burning sensation in the tongue among other symptoms.
    • Erythema multiforme: A rare skin condition that can also affect the mucous membranes, leading to oral lesions and a burning sensation.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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