Differential Diagnosis for Constant Sensation of Swallowing

• Single most likely diagnosis
  • Globus pharyngeus: This condition is characterized by a persistent, non-painful sensation of having a lump or foreign body in the throat, which can be described as a constant sensation of swallowing. It is often associated with anxiety, stress, or gastroesophageal reflux disease (GERD).
• Other Likely diagnoses
  • Gastroesophageal reflux disease (GERD): GERD can cause a sensation of swallowing or a feeling of something being stuck in the throat due to the reflux of stomach acid into the esophagus.
  • Esophageal dysmotility: Abnormal movement of the esophagus can lead to difficulty swallowing and a sensation of constant swallowing.
  • Anxiety or stress: High levels of anxiety or stress can cause or exacerbate the sensation of constant swallowing.
• Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
  • Esophageal cancer: Although rare, esophageal cancer can cause difficulty swallowing and a sensation of something being stuck in the throat.
  • Thyroid disorders: Certain thyroid conditions, such as a thyroid nodule or goiter, can cause compression of the esophagus, leading to swallowing difficulties.
• Rare diagnoses
  • Eosinophilic esophagitis: A rare inflammatory condition of the esophagus that can cause difficulty swallowing and a sensation of food getting stuck.
  • Zenker's diverticulum: A rare condition where a pouch forms in the pharynx, which can cause difficulty swallowing and a sensation of food getting stuck.
  • Pharyngeal or esophageal foreign body: Although rare, a foreign body lodged in the throat or esophagus can cause a constant sensation of swallowing.