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Differential Diagnosis for Pupil Dilated with Blurry Vision

Single Most Likely Diagnosis

  • Acute Angle-Closure Glaucoma: This condition is characterized by a sudden increase in intraocular pressure, which can cause pupil dilation and blurry vision. It is a medical emergency that requires prompt treatment to prevent permanent vision loss.

Other Likely Diagnoses

  • Ocular Migraine: Migraines can cause visual disturbances, including blurry vision and pupil dilation, due to the temporary alteration of blood flow to the brain and eyes.
  • Anticholinergic Toxicity: Medications or substances with anticholinergic properties can cause pupil dilation (mydriasis) and blurry vision by blocking the action of acetylcholine in the eye.
  • Traumatic Iris Damage: Injury to the iris can lead to pupil dilation and vision problems, including blurriness.

Do Not Miss Diagnoses

  • Stroke or Transient Ischemic Attack (TIA): Although less common, a stroke or TIA can present with sudden visual disturbances, including blurry vision and pupil changes. Early recognition is crucial for timely intervention.
  • Pituitary Apoplexy: A rare but potentially life-threatening condition where a pituitary tumor suddenly hemorrhages or infarcts, leading to acute symptoms that can include visual disturbances and pupil abnormalities.
  • Cavernous Sinus Thrombosis: A serious condition involving a blood clot in the cavernous sinus, which can cause a range of symptoms including visual disturbances, due to its proximity to several cranial nerves.

Rare Diagnoses

  • Adie Syndrome: A rare neurological disorder characterized by a tonic pupil (which can appear dilated) and reduced or absent deep tendon reflexes. It typically affects young women.
  • Sympathetic Ophthalmia: A rare, inflammatory condition that can occur after penetrating eye injury, leading to symptoms in the uninjured eye, including vision changes and pupil reactions.
  • Third Cranial Nerve (Oculomotor Nerve) Palsy: While not extremely rare, when it presents with pupil dilation, it often indicates a more serious underlying cause, such as an aneurysm, which makes it important to investigate thoroughly.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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