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Last updated: October 9, 2025View editorial policy

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Differential Diagnosis for Tristan's Sore Tummy

Given Tristan's symptoms and medical history, the following differential diagnoses can be considered:

  • Single most likely diagnosis
    • Gastroenteritis: This is a common condition that can cause a sore tummy and is often self-limiting. The fact that Tristan has no other specific concerns or symptoms and is experiencing this for the first time makes a viral or bacterial gastrointestinal infection a plausible explanation.
  • Other Likely diagnoses
    • Side effects of Cabenuva injections: Although Tristan is undergoing HIV treatment with Cabenuva, gastrointestinal side effects can occur with any medication, including antiretroviral therapy. It's possible that the sore tummy is related to the treatment.
    • Irritable Bowel Syndrome (IBS): Given the lack of other symptoms, IBS could be considered, especially if Tristan experiences recurring abdominal pain or changes in bowel habits.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • HIV-related opportunistic infections (e.g., CMV colitis, MAC infection): Although Tristan is on treatment, the possibility of an opportunistic infection, especially if his viral load is not well controlled, cannot be overlooked.
    • Gastrointestinal malignancy: Although rare, especially in someone with a relatively recent HIV diagnosis, the possibility of a gastrointestinal cancer (e.g., lymphoma) should be considered, particularly if other risk factors are present.
    • Acute abdomen (e.g., appendicitis, perforated viscus): These conditions require immediate medical attention and can present with nonspecific abdominal pain.
  • Rare diagnoses
    • Inflammatory bowel disease (e.g., Crohn's disease, ulcerative colitis): These conditions are less common but can cause chronic abdominal symptoms.
    • Pancreatitis: Although less likely without other symptoms like severe pain or vomiting, pancreatitis can occur and needs to be considered, especially if Tristan has risk factors such as hypertriglyceridemia or gallstones.
    • Medication-induced pancreatitis or hepatitis: Some antiretroviral medications can cause pancreatitis or hepatitis, although this is rare with Cabenuva.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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