Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 9, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Epigastric Pain Radiating to Right Elbow

Single Most Likely Diagnosis

  • Gallbladder disease (cholecystitis or cholelithiasis): The pain radiating from the epigastric area to the right elbow is a classic presentation for gallbladder disease, particularly when the pain is severe and persistent. The referred pain to the right elbow is due to the shared nerve roots (T6-T9) that innervate both the gallbladder and the elbow.

Other Likely Diagnoses

  • Peptic ulcer disease: Epigastric pain is a common symptom of peptic ulcers, and while the pain typically remains in the epigastric area, it can radiate to the back or, less commonly, to other areas including the elbow in some cases.
  • Pancreatitis: Acute pancreatitis can cause severe epigastric pain that radiates to the back and, in some instances, may be referred to other areas due to the inflammatory process affecting nearby structures.

Do Not Miss Diagnoses

  • Myocardial infarction: Although less common, myocardial infarction (heart attack) can present with epigastric pain, especially in women, and the pain can radiate to various parts of the body, including the arms. Missing this diagnosis can be fatal.
  • Pulmonary embolism: While the primary symptom is usually dyspnea, in some cases, pulmonary embolism can present with chest pain that might be referred to as epigastric and radiate to the arms, making it a critical diagnosis not to miss.
  • Aortic dissection: This is a life-threatening condition where the inner layer of the aorta tears. The pain is often described as severe and tearing, typically starting in the chest and radiating to the back or abdomen, but can be referred to other areas.

Rare Diagnoses

  • Diabetic radiculopathy: Diabetes can cause nerve damage leading to radiculopathy, which might result in pain patterns that are atypical, including epigastric pain radiating to unusual areas like the elbow.
  • Intra-abdominal malignancies: Certain cancers, like pancreatic cancer, can cause epigastric pain that might radiate to other areas, including the back or, less commonly, to the arms. These conditions are less common but should be considered in the differential diagnosis, especially in patients with risk factors or other suggestive symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.