What are the differential diagnoses for tachycardia (rapid heart rate) in the absence of atrial fibrillation (afib) on electrocardiogram (EKG)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: March 23, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Tachycardia Differentials

Given the presentation of tachycardia without atrial fibrillation (AFib) on EKG, the differential diagnoses can be categorized as follows:

  • Single Most Likely Diagnosis

    • Sinus Tachycardia: This is the most common cause of tachycardia and can be due to various factors such as anxiety, stress, dehydration, fever, or physical exertion. It is characterized by a rapid heart rate with a regular rhythm and a P wave preceding each QRS complex.
  • Other Likely Diagnoses

    • Supraventricular Tachycardia (SVT): This includes conditions like atrioventricular nodal reentrant tachycardia (AVNRT) and atrioventricular reentrant tachycardia (AVRT), which are characterized by a sudden onset of a rapid heart rate, often with a narrow QRS complex.
    • Ventricular Tachycardia (VT): Although less common than SVT, VT is a significant consideration, especially in patients with underlying heart disease. It is characterized by a series of three or more consecutive premature ventricular contractions at a rate faster than 100 beats per minute.
    • Atrial Flutter: This condition is characterized by a rapid but regular atrial rhythm, often with a 2:1 or 3:1 block, resulting in a regular ventricular rate.
  • Do Not Miss Diagnoses

    • Cardiac Tamponade: Although rare, cardiac tamponade can present with tachycardia and is a life-threatening condition that requires immediate intervention. It is characterized by the accumulation of fluid in the pericardial sac, leading to impaired cardiac filling.
    • Pulmonary Embolism (PE): A significant and potentially life-threatening condition that can present with tachycardia among other symptoms like dyspnea and chest pain.
    • Hypovolemic Shock: Severe dehydration or blood loss can lead to tachycardia as a compensatory mechanism to maintain cardiac output.
    • Thyrotoxicosis: Hyperthyroidism can cause tachycardia due to the excess of thyroid hormones, which increase the body's metabolic rate.
  • Rare Diagnoses

    • Wolff-Parkinson-White (WPW) Syndrome: A rare condition characterized by an accessory electrical pathway between the atria and ventricles, leading to tachycardia.
    • Junctional Tachycardia: A rare condition where the atrioventricular junction acts as an ectopic pacemaker, leading to a rapid heart rate.
    • Idiopathic Ventricular Tachycardia: A rare condition where VT occurs in the absence of structural heart disease, often originating from the right ventricular outflow tract.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.