Alternative Name for Ductus Endolymphaticus
The alternative name for ductus endolymphaticus is the endolymphatic duct. 1, 2
Anatomical Context and Significance
- The endolymphatic duct is a tubular structure that connects the endolymphatic sac to the vestibular system of the inner ear 1
- It plays a critical role in endolymph homeostasis and is often implicated in the pathophysiology of Ménière's disease 1
- The isthmus portion of the endolymphatic duct is particularly significant, as diminution of its width has been observed in temporal bones from patients with Ménière's disease 1
Clinical Relevance
- Dysfunction of the endolymphatic duct is associated with endolymphatic hydrops, which is the morphological substrate of Ménière's disease 3
- Surgical interventions targeting the endolymphatic duct, such as endolymphatic duct blockage (EDB), have been developed for the treatment of refractory Ménière's disease 4
- Endolymphatic duct blockage involves obstructing the endolymphatic duct with surgical clips and has shown promising results for controlling vertigo symptoms 5
Imaging Considerations
- High-resolution T2-weighted fast spin-echo (FSE) MR imaging can be used to evaluate the endolymphatic duct and associated structures 2
- Large endolymphatic duct and sac (LEDS) is one of the most common anomalies seen in patients with congenital sensorineural hearing loss 2
- MRI of the internal auditory canal with specialized techniques can demonstrate accumulation of gadolinium in the endolymphatic sac in patients with Ménière's disease 6
Anatomical Variations and Abnormalities
- The endolymphatic duct may show variations in size and shape, with a large endolymphatic duct and sac (LEDS) being a recognized congenital anomaly 2
- LEDS is frequently associated with other inner ear anomalies, including cochlear and vestibular dysplasia 2
- Pathological changes in the endolymphatic duct, such as fibrotic changes in the perisaccular loose connective tissue, have been observed in temporal bone studies of patients with Ménière's disease 1