What are the recommended procedures for pre-operative (pre-op) screening?

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Recommended Procedures for Pre-Operative Screening

Preoperative testing should be based on the patient's clinical history, comorbidities, physical examination findings, and perioperative risk assessment rather than performed routinely for all patients. 1

Cardiovascular Assessment

  • Electrocardiography (ECG) is recommended for patients with signs or symptoms of cardiovascular disease 1
  • ECG is indicated for patients undergoing high-risk surgery and those undergoing intermediate-risk surgery who have additional risk factors (coronary heart disease, structural heart disease, heart failure, cerebrovascular disease, diabetes, or renal impairment) 2
  • Patients undergoing low-risk surgery do not require ECG 1
  • Risk stratification should identify active cardiac conditions requiring evaluation before surgery (unstable coronary syndromes, decompensated heart failure, significant arrhythmias, severe valvular disease) 2
  • Patients with good functional capacity (≥4 METs or ability to climb ≥2 flights of stairs) can generally proceed to surgery without further cardiac testing 2, 3

Pulmonary Assessment

  • Chest radiography is not recommended routinely for asymptomatic, otherwise healthy patients 1
  • Chest radiography is indicated for patients with new or unstable cardiopulmonary signs or symptoms 1
  • Consider chest radiography for patients at risk of postoperative pulmonary complications if results would change perioperative management 1

Laboratory Testing

Complete Blood Count (CBC)

  • CBC is indicated for patients with diseases that increase risk of anemia (liver disease, hematologic disorders) 1
  • CBC is recommended for patients with history of anemia or recent blood loss 1
  • CBC should be performed when significant perioperative blood loss is anticipated 1
  • CBC is indicated for patients undergoing cardiovascular surgery and specific high-risk procedures 1

Electrolytes and Renal Function

  • Electrolyte and creatinine testing should be reserved for patients at risk of electrolyte abnormalities or renal impairment 1
  • Testing is recommended for patients taking medications that predispose to electrolyte abnormalities (diuretics, ACE inhibitors, ARBs, NSAIDs, digoxin) 1
  • Patients with hypertension, heart failure, chronic kidney disease, complicated diabetes mellitus, or liver disease should have electrolyte and creatinine testing 1
  • Electrolyte measurement is recommended for all patients with known renal conditions and those undergoing neurosurgery or cardiovascular surgery 1

Glucose and A1C Testing

  • Random glucose testing should be performed in patients at high risk of undiagnosed diabetes mellitus 1
  • In patients with diagnosed diabetes, A1C testing is recommended only if results would change perioperative management 1
  • The incidence of occult diabetes in the presurgical population is low (0.5%), so universal screening is not justified 1

Coagulation Studies

  • Coagulation testing (prothrombin time, activated partial thromboplastin time, platelet count) should be reserved for patients with history of bleeding or medical conditions predisposing to coagulopathy (e.g., liver disease) 1
  • Testing is indicated for patients taking anticoagulants 1
  • Indiscriminate preoperative coagulation testing is not warranted due to low prevalence of inherited coagulopathies 1

Urinalysis

  • Routine urinalysis is not recommended for asymptomatic patients 1
  • Urinalysis is indicated for patients undergoing urologic procedures or implantation of foreign material (e.g., prosthetic joint, heart valve) 1

Timing of Testing

  • For relatively healthy patients (ASA physical status I-II), laboratory testing performed up to 2 months before surgery does not increase risk of 30-day morbidity and mortality, suggesting retesting shortly before surgery is unnecessary 4
  • Testing performed 2-3 months before surgery may be associated with increased risk compared to testing within 2 months 4

Special Considerations

  • Patients in their usual state of health undergoing cataract surgery do not require preoperative testing 1
  • Older adults (≥75 years) and patients with coronary stents have higher risk of perioperative myocardial infarction and major adverse cardiovascular events, warranting careful preoperative consideration 3
  • Routine perioperative use of high-dose β-blockers shortly before surgery is associated with higher risk of stroke and mortality and should not be routinely used 3

Cost Considerations

  • Approximately $18 billion is spent annually on preoperative testing in the US, with significant potential for waste reduction 5
  • Eliminating unnecessary testing reduces costs without compromising safety and quality of care 6

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Preoperative Cardiac Evaluation for Intermediate-Risk Surgeries

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Preoperative laboratory testing: Implications of "Choosing Wisely" guidelines.

Best practice & research. Clinical anaesthesiology, 2020

Research

Preoperative assessment.

Lancet (London, England), 2003

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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