Is Escherichia coli (E. coli) a gram-negative bacillus?

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Last updated: February 11, 2025View editorial policy

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From the Guidelines

Yes, Escherichia coli (E. coli) is a gram-negative bacillus.

Characteristics of E. coli

  • E. coli is a type of Enterobacteriaceae, a family of gram-negative bacteria 1
  • It is a facultative and aerobic organism, meaning it can live with or without oxygen 1
  • E. coli is commonly found in the human gut and can cause infections in various parts of the body, including the abdomen 1

Prevalence of E. coli in Infections

  • E. coli is one of the most common pathogens isolated from intra-abdominal infections, particularly those derived from the colon 1
  • It is often found in combination with other bacteria, such as anaerobes like Bacteroides fragilis 1

Antibiotic Resistance

  • E. coli has developed resistance to various antibiotics, including ampicillin/sulbactam, fluoroquinolones, and extended-spectrum beta-lactamases 1
  • The choice of antibiotic therapy should be based on local microbiologic data, cost, allergies, and formulary availability 1

From the Research

Characteristics of Escherichia coli

  • Escherichia coli (E. coli) is classified as a gram-negative bacillus 2, 3
  • It is a rod-shaped bacterium in the family Enterobacteriaceae 3
  • E. coli is a facultative, anaerobic Gram-negative rod 4

Classification and Identification

  • E. coli can be differentiated from other gram-negative bacteria using PCR-based tests 5
  • The assay employs primers derived from the nucleotide sequences flanking the gene encoding the universal stress protein (uspA) 5

Ecological Role

  • E. coli plays an important ecological role and can be used as a bioindicator of antimicrobial resistance 4
  • It is a resident of the normal intestinal microbiota, but some strains can cause diseases in humans, other mammals, and birds 2

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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