What are the recommended doses of Tylenol (acetaminophen) and Motrin (ibuprofen) for a 44-pound child?

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Acetaminophen and Ibuprofen Dosing for a 44-Pound Child

For a 44-pound (20 kg) child, the recommended dose of acetaminophen is 200-300 mg every 4-6 hours, and the recommended dose of ibuprofen is 100-200 mg every 6-8 hours. 1, 2

Acetaminophen (Tylenol) Dosing

  • Acetaminophen should be dosed at 10-15 mg/kg per dose 1, 3
  • For a 44-pound (20 kg) child, this equals 200-300 mg per dose
  • Maximum of 4 doses in 24 hours (every 4-6 hours) 2
  • Available in liquid suspensions/elixirs, chewable tablets, and regular tablets 1
  • Use appropriate measuring devices for liquid formulations to ensure accurate dosing 1
  • Children weighing more than 40 kg should be dosed as adults 1

Ibuprofen (Motrin) Dosing

  • Ibuprofen should be dosed at 5-10 mg/kg per dose 2, 4
  • For a 44-pound (20 kg) child, this equals 100-200 mg per dose
  • Maximum of 3 doses in 24 hours (every 6-8 hours) 2
  • Ibuprofen has a longer duration of action than acetaminophen 2

Important Considerations

  • Weight-based dosing is more accurate than age-based dosing for both medications 5, 4
  • Parents who use weight-based dosing are less likely to give inaccurate doses of medication 4
  • Studies show that up to 51% of parents give inaccurate doses of these medications, with acetaminophen more frequently misdosed (62%) than ibuprofen (26%) 4
  • Carefully record all dose times to avoid accidentally exceeding the maximum recommended dose 2

If Using Both Medications

  • When treating fever, ibuprofen may be used first due to its longer duration of action 2
  • If using both medications, consider the relative risks (potentially exceeding maximum recommended doses) versus benefits (additional fever-free time) 2
  • Always record dose times carefully to avoid accidental overdosing 2

Dosing Accuracy

  • Use appropriate measuring devices for liquid formulations 1
  • Avoid using household spoons which can lead to significant dosing errors 5, 4
  • For acetaminophen, inadequate dosing may result in insufficient fever control, while excessive dosing can lead to hepatotoxicity 6, 5
  • For ibuprofen, accurate dosing is essential to balance effectiveness with minimizing side effects 2, 4

References

Guideline

Acetaminophen Dosing Guidelines for Children

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Pediatric dosing of acetaminophen.

Pediatric pharmacology (New York, N.Y.), 1983

Research

Acetaminophen and ibuprofen dosing by parents.

Pediatric emergency care, 2000

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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