Urinary Tract Infection (UTI): This is often the most common cause of discomfort or pressure during urination, especially in women. Symptoms can include dysuria (painful urination), frequent urination, and sometimes abdominal or pubic pressure.

Benign Prostatic Hyperplasia (BPH): In men, an enlarged prostate can cause pressure during urination due to obstruction of the urethra.
Urethral Stricture: Narrowing of the urethra can cause difficulty and pain during urination, leading to a feeling of pressure.
Kidney Stones: While often associated with severe back pain, kidney stones can also cause discomfort or pressure in the pubic area, especially if they are moving down the ureters.

Bladder Cancer: Although less common, bladder cancer can cause symptoms similar to a UTI, including pain or pressure during urination. It's crucial to rule out cancer, especially in smokers or those with a family history.
Prostate Cancer: In men, prostate cancer can cause urinary symptoms similar to BPH, including pressure during urination. Early detection is key for effective treatment.
Septicemia or Sepsis from a UTI: If a UTI progresses to sepsis, it can be life-threatening. Symptoms might include high fever, chills, and severe pain, in addition to urinary symptoms.

Interstitial Cystitis: A chronic condition causing bladder pressure, bladder pain, and sometimes pelvic pain. The symptoms can worsen as the bladder fills and may improve with urination.
Schistosomiasis (Bilharzia): A parasitic infection that can cause urinary symptoms, including pain and pressure during urination, especially in individuals who have traveled to or lived in areas where the disease is common.
Malacoplakia: A rare inflammatory condition that can affect the urinary tract and cause symptoms similar to a UTI, including pressure during urination.