Lifitegrast 5% Ophthalmic Solution Price in India
Lifitegrast 5% ophthalmic solution is not currently listed in any of the provided evidence with specific pricing information for India. The available evidence focuses on clinical efficacy, safety profiles, and US/Canadian pricing data, but does not contain information about pricing in the Indian market.
Available Information on Lifitegrast
Mechanism and Indications
- Lifitegrast is a lymphocyte function-associated antigen-1 (LFA-1) antagonist that blocks the interaction between LFA-1 and intercellular adhesion molecule 1 (ICAM-1), reducing T-cell mediated inflammation in dry eye disease 1
- It was FDA-approved in 2016 for treating signs and symptoms of dry eye disease 1
Clinical Uses
- Primarily used for moderate to severe dry eye disease that has had inadequate response to artificial tears 1
- Also used for contact lens-induced dry eye (91.7% of surveyed providers) and dry eye before/after refractive or cataract surgery (83.3%) 2
- Can be used as an alternative to cyclosporine for patients with refractory dry eye disease 1
Efficacy
- Shows significant improvement in both signs (corneal and conjunctival staining) and symptoms (eye dryness scores) over 3 months of treatment 1, 3
- In clinical trials, lifitegrast improved inferior corneal staining scores and eye dryness scores compared to placebo 3
- Real-world provider satisfaction with lifitegrast efficacy was rated moderately high (mean 6.6 on a 10-point scale) 2
Safety Profile
- Generally well-tolerated in 12-month safety studies 4
- Most common adverse events include instillation site irritation (burning), instillation site reaction, reduced visual acuity, and dysgeusia (change in taste) 4
- No serious ocular adverse events were reported in clinical trials 4
Pricing Information in Other Markets
While specific Indian pricing is not available in the evidence, US pricing information shows:
- In the US market, prescription medications for dry eye disease generally range from $289-$1,497 for a 30-day supply, based on data for other ophthalmic medications 5
- Cyclosporine (which lifitegrast can be an alternative to) has been noted to have potential for malabsorption issues and is listed at approximately $556-$703 for a 30-day supply in the US 5
Conclusion for Indian Market
Without specific pricing data for India in the provided evidence, it's not possible to provide the exact cost of lifitegrast 5% ophthalmic solution in India. To obtain accurate pricing information, patients should:
- Consult with local ophthalmologists who prescribe the medication
- Check with pharmaceutical distributors in India
- Contact the manufacturer's Indian subsidiary or distributor
- Check online pharmacy platforms that operate in India
The medication may be available under different brand names in the Indian market or may not yet be available, as the evidence does not confirm its regulatory status in India.