Benign Essential Blepharospasm: This is the most common cause of eye twitching, characterized by involuntary spasms of the eyelid muscles. It is often related to fatigue, stress, or caffeine consumption.

Dry Eye Syndrome: Irritation and inflammation of the eyes can cause twitching, especially if the eyes are not producing enough tears.
Eye Strain: Prolonged use of computers, reading, or other activities that cause eye fatigue can lead to twitching.
Caffeine or Alcohol Withdrawal: Sudden cessation of caffeine or alcohol consumption can cause eye twitching among other symptoms.
Nutritional Deficiencies: Deficiencies in magnesium, potassium, or other essential nutrients can contribute to muscle twitching, including the eyes.

Multiple Sclerosis: Although rare, multiple sclerosis can cause eye twitching as part of its broader neurological symptoms. Early diagnosis is crucial for effective management.
Thyroid Disorders: Both hyperthyroidism and hypothyroidism can cause muscle twitching, including the eyes, due to the metabolic effects of thyroid hormones on the body.
Botulism: A rare but serious condition caused by a toxin that can lead to muscle weakness, including eyelid twitching, and potentially life-threatening respiratory failure if not treated promptly.

Hemifacial Spasm: A rare neurological disorder characterized by involuntary muscle spasms on one side of the face, including the eye.
Blepharospasm associated with Dystonia: A condition where involuntary muscle contractions cause repetitive movements or abnormal postures, including eye twitching.
Neurodegenerative Diseases: Such as Parkinson's disease or Huntington's disease, which can have eye twitching as one of the many symptoms, though it's not a primary or early manifestation in most cases.