Differential Diagnosis for a 77yo with Sore Throat without Fevers or Cough
Single Most Likely Diagnosis
- Viral Pharyngitis: This is the most common cause of sore throat in adults, often without systemic symptoms like fever or cough, especially in the elderly who may have a blunted immune response.
Other Likely Diagnoses
- Gastroesophageal Reflux Disease (GERD): Can cause sore throat due to acid reflux, especially in the morning or after eating certain foods.
- Allergic Rhinitis: Postnasal drip from allergies can irritate the throat, leading to soreness.
- Dry Mouth (Xerostomia): Common in the elderly, especially those with decreased saliva production due to medications or other conditions, leading to throat discomfort.
- Irritants: Exposure to smoke, pollution, or other environmental irritants can cause throat soreness.
Do Not Miss Diagnoses
- Streptococcal Pharyngitis: Although less likely without fever, it's crucial to consider and rule out due to the potential for complications like rheumatic fever or glomerulonephritis.
- Epiglottitis: A medical emergency that can present with severe sore throat, though typically accompanied by other symptoms like difficulty swallowing or shortness of breath.
- Lemierre's Syndrome: A rare but serious condition following a sore throat, characterized by jugular vein thrombosis and septicemia, often due to Fusobacterium necrophorum.
- Oral or Pharyngeal Cancer: Especially in elderly patients with risk factors like smoking or alcohol use, a persistent sore throat can be an early symptom.
Rare Diagnoses
- Diphtheria: Although rare in vaccinated populations, it can cause a severe sore throat with a characteristic membrane.
- Infectious Mononucleosis: Caused by Epstein-Barr virus, can present with sore throat, though typically accompanied by fever, fatigue, and lymphadenopathy.
- Tuberculosis: Can cause a chronic sore throat, especially in immunocompromised individuals or those from endemic areas.
- Sjögren's Syndrome: An autoimmune disorder that can cause dry mouth and throat, leading to soreness.