How should insulin doses be adjusted when sending a patient with diabetes home?

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Last updated: October 12, 2025View editorial policy

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Insulin Adjustment Guidelines for Patients Discharged from Hospital

When sending a patient with diabetes home from the hospital, insulin doses should be adjusted to match their home routine, with patients generally returning to their pre-hospitalization insulin regimen unless significant improvements in glycemic control were achieved during hospitalization with a modified regimen. 1

General Principles for Insulin Adjustment at Discharge

  • For patients with well-controlled diabetes before hospitalization, return to their pre-hospitalization insulin regimen upon discharge 1
  • For patients with poor pre-admission glycemic control (high A1C levels), consider maintaining the improved hospital regimen if it demonstrated better control 1
  • Provide detailed written instructions about the insulin regimen, including timing, dosage, and adjustment algorithms 2
  • Ensure the patient has adequate supplies of insulin and monitoring equipment before discharge 2

Specific Insulin Adjustment Recommendations

For Patients on Basal-Bolus Regimens:

  • Maintain the same distribution of approximately 50% basal insulin and 50% prandial insulin in the total daily dose 2
  • For patients who will have increased physical activity at home compared to the hospital, consider reducing the total insulin dose by 10-20% to prevent hypoglycemia 1
  • Adjust basal insulin doses based on fasting glucose values and prandial insulin based on both pre- and post-meal glucose values 1
  • Continue basal insulin at the same time each day to maintain consistent blood glucose control 3

For Patients on Insulin Pumps:

  • Ensure patients have adequate pump supplies including extra batteries 1
  • Review any adjustments made to basal rates, insulin-to-carbohydrate ratios, or correction factors during hospitalization 1
  • Document these changes clearly in discharge instructions 1

Documentation and Communication

  • Provide a clear record of the insulin regimen used during hospitalization and any adjustments made for discharge 1
  • Send a copy of this record to the patient's primary care provider or endocrinologist 1
  • Document the rationale for any major changes to the insulin regimen 1

Patient Education Before Discharge

  • Teach patients how to monitor blood glucose and adjust insulin doses based on results 1
  • Instruct on carbohydrate counting and food choices to balance with insulin dosing 1
  • Provide education on recognizing and treating hypoglycemia 4
  • Ensure patients understand when to contact their healthcare provider for assistance with insulin adjustments 2

Common Pitfalls to Avoid

  • Avoid using sliding scale insulin alone without basal insulin after discharge, as this leads to poor glycemic control 4
  • Avoid abrupt discontinuation of insulin when transitioning from hospital to home, as this can lead to rebound hyperglycemia 5
  • Avoid withholding basal insulin when blood glucose is in normal range (>100 mg/dL), as this disrupts glycemic stability 3
  • Avoid making major changes to insulin type or regimen without discussing with the patient and their regular diabetes provider 1

Special Considerations

  • For patients who experienced frequent hypoglycemia in the hospital, consider reducing insulin doses by 10-20% at discharge 1
  • For patients with varying daily routines or physical activity levels, provide specific instructions on how to adjust insulin doses accordingly 2
  • For elderly patients or those with cognitive impairment, simplify the regimen when possible and ensure adequate support for insulin administration 3
  • For patients with renal or hepatic dysfunction, insulin doses may need to be reduced due to decreased clearance 6

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Insulina Therapy for Patients with Type 1 Diabetes

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Management of Basal Insulin with Elevated Blood Sugar

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Insulin Administration Guidelines for Hospitalized Patients with Hyperglycemia

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

EADSG Guidelines: Insulin Therapy in Diabetes.

Diabetes therapy : research, treatment and education of diabetes and related disorders, 2018

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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