From the Research
Statins may have a mild effect on libido, but the evidence is not strong enough to suggest a significant impact on sexual function in most individuals, and the benefits of statins in reducing cardiovascular risk generally outweigh the potential risks to libido. When considering the effect of statins on libido, it's essential to weigh the benefits of statin therapy in reducing cardiovascular risk against the potential risks to sexual function. According to a study published in 2021 1, atorvastatin may reduce total testosterone levels in females with polycystic ovary syndrome (PCOS), but the evidence is not strong enough to suggest a significant impact on sexual function in most individuals.
Key Points to Consider
- The potential mechanism for libido changes may involve statins' effects on testosterone production, as cholesterol is a precursor to sex hormones 1.
- Some statins can cause muscle pain or fatigue, which might indirectly impact sexual desire 2.
- The benefits of statins in reducing cardiovascular risk generally outweigh the potential risks to libido, but open communication with a healthcare provider is essential to find the right balance between treating high cholesterol and maintaining sexual function.
- If experiencing decreased sexual desire while taking statins, discuss this with a healthcare provider to determine if the statin is responsible, and consider alternative statins or cholesterol-lowering medications if necessary.
Clinical Implications
- Healthcare providers should be aware of the potential effects of statins on libido and monitor patients for any changes in sexual function.
- Patients experiencing decreased sexual desire while taking statins should not stop taking their medication without medical guidance.
- Alternative statins or cholesterol-lowering medications may be considered if libido changes are a concern, but the decision should be made on a case-by-case basis, taking into account the individual's cardiovascular risk and overall health.