Recommended Dosage of Dicycloverine for Children
Dicycloverine (Dicyclomine) is not recommended for use in children under 6 months of age due to safety concerns.
Age-Based Dosing Recommendations
Infants and Young Children
- Dicycloverine is contraindicated in infants less than 6 months of age due to risk of serious adverse effects 1
- Not recommended for use in children under 2 years of age due to limited safety and efficacy data 1
Children 2-12 years
Adolescents (>12 years)
Administration Considerations
- Administer before meals and at bedtime for optimal effect 1
- Oral solution formulation is preferred for younger children who may have difficulty swallowing tablets 1
- Dosage should be started at the lower end of the recommended range and titrated based on response 1
Safety Considerations
Contraindications
- Infants less than 6 months of age 1
- Hypersensitivity to dicycloverine or any component of the formulation 1
- Obstructive gastrointestinal or urinary conditions 1
- Glaucoma 1
Adverse Effects to Monitor
- Anticholinergic effects: dry mouth, blurred vision, urinary retention 1
- Central nervous system effects: drowsiness, dizziness 1
- Cardiovascular effects: tachycardia, palpitations 1
Drug Interactions
- Potential interaction with other anticholinergic medications, which may increase anticholinergic effects 1
- Caution with concomitant use of hydrochlorothiazide, which may lead to contraction alkalosis 1
Monitoring
- Monitor for signs of anticholinergic toxicity, especially in younger children 1
- Assess for clinical improvement of symptoms 1
- Discontinue if adverse effects outweigh benefits 1
Important Cautions
- Pediatric dosing should be carefully calculated based on age and weight 2
- Avoid use in conditions where anticholinergic effects may be harmful (e.g., fever, autonomic neuropathy) 1
- Dicycloverine should be used with caution in children with Down syndrome, who may be more sensitive to anticholinergic effects 1