Recurrent or Persistent Hepatitis: Given the patient's history of drug-induced hepatitis 2 months prior, it's plausible that the hepatitis has either recurred or persisted, especially if the causative agent (e.g., a drug) was not fully discontinued or if there was an underlying susceptibility to liver injury. The jaundiced eyes (indicative of bilirubin buildup) and elevated temperature support an ongoing liver issue.

Sickle Cell Crisis: Although less common in a patient without a known history of sickle cell disease, the painful extremities and jaundice could suggest a hemolytic crisis, especially if the patient has a previously undiagnosed hemoglobinopathy.
Autoimmune Hemolytic Anemia (AIHA): This condition could explain the jaundice (due to hemolysis) and potentially the painful extremities if there's an associated autoimmune component affecting joints.
Infection: Given the elevated temperature, an infectious process (e.g., viral or bacterial) affecting the liver or joints could be considered, especially if the patient has been exposed to pathogens or has a compromised immune system.

Wilson's Disease: A genetic disorder leading to copper accumulation in the liver, which can cause liver dysfunction and hemolysis. It's crucial to consider this diagnosis due to its potential for severe liver damage and the need for specific treatment.
Hemophagocytic Lymphohistiocytosis (HLH): A rare but life-threatening condition characterized by excessive immune activation, which can lead to liver dysfunction, coagulopathy, and multi-organ failure. The presence of fever, jaundice, and potentially cytopenias would necessitate consideration of HLH.
Malignancy: Although less likely, certain malignancies (e.g., lymphoma) can present with systemic symptoms including fever, joint pain, and liver dysfunction.

Primary Biliary Cholangitis (PBC): An autoimmune disease of the liver characterized by progressive destruction of the bile ducts within the liver, leading to cholestasis and, potentially, jaundice. It's less common in young individuals but should be considered in the differential for chronic liver disease.
Primary Sclerosing Cholangitis (PSC): A chronic liver disease characterized by inflammation and fibrosis of the bile ducts, which could explain the jaundice and potentially the history of cholecystectomy if there were underlying bile duct issues.

Given the complexity of the patient's presentation and history, admission for further evaluation and monitoring is recommended. This would allow for:

Detailed laboratory tests (including liver function tests, complete blood count, and potentially autoimmune and infectious disease panels).
Imaging studies (e.g., ultrasound or MRI of the liver) to assess liver morphology and rule out complications.
Consultation with specialists (gastroenterologist, hepatologist, or rheumatologist) to guide further management.
Observation for potential deterioration, especially if a severe condition like HLH or Wilson's Disease is considered.