Proper Examination and Management of the Urethral Meatus for Diagnostic Purposes
The examination of the urethral meatus should include visual inspection for abnormalities, assessment for blood or discharge, and appropriate diagnostic imaging when urethral injury is suspected, with retrograde urethrography being the procedure of choice for suspected trauma and urethroscopy preferred for penile lesions.
Initial Assessment of the Urethral Meatus
Visual Examination
- Carefully inspect the external urethral meatus for visible abnormalities including swelling, ecchymosis, discharge, blood, stenosis, or anatomical variations 1
- In males, draw back the prepuce to avoid contamination when examining the meatus 1
- In females, clean the introitus using a sterile gauze swab before examination 1
- Look for signs of trauma such as blood at the meatus, which is a critical indicator of potential urethral injury 1
Key Clinical Findings to Document
- Presence of vesicular or ulcerative lesions on the genitals 1
- Mucous or purulent discharge from the meatus 1
- Abnormal meatal position, size, or shape 2
- Signs of inflammation, stenosis, or caruncle formation 3
- In trauma cases, assess for penile ecchymosis, swelling, or scrotal hematoma 1
Diagnostic Approach Based on Clinical Scenario
For Suspected Urethral Trauma
- Blood at the urethral meatus after trauma requires immediate retrograde urethrography 1
- Avoid blind catheterization before imaging in trauma cases as this may worsen urethral injuries 1
- In patients with pelvic fractures and blood at the meatus, always evaluate for urethral injury before bladder catheterization 1
- For penile injuries, urethroscopy is preferred over retrograde urethrography 1
For Suspected Urethral Stenosis
- Assess for symptoms of obstruction: abnormal urine stream direction, dysuria, frequency, prolonged urination 4
- Uroflowmetry should be performed to identify bladder outlet obstruction patterns 5
- In children with suspected meatal stenosis, calibration of the urethral meatus may be necessary 5
For Suspected Infection or STIs
- Collect urethral exudates for testing by inserting a cotton-wool or Dacron swab into the external urethral meatus (0.5-2 cm depth) 1
- For vesicular lesions, open vesicles with a sterile needle and collect content with a swab for testing 1
- Apply collected material to microscope slides for immunofluorescence staining or place in transport media for viral culture or nucleic acid amplification tests 1
Proper Specimen Collection Techniques
Male Urethral Sampling
- Clean the external urethral opening region with a saline-moistened swab 1
- Insert a cotton-wool or Dacron swab carefully into the external urethral meatus to a depth of 0.5–2 cm 1
- Collect urethral exudates for appropriate testing 1
Female Urethral Sampling
- Clean the introitus using a sterile gauze swab 1
- Insert a cotton-wool or Dacron swab on an aluminum shaft into the urethra to a depth of 0.5 cm 1
- For vaginal examination, insert a vaginal speculum and clean the cervical canal opening with a sterile gauze swab 1
Urine Collection
- First-catch urine (first 10-20 ml) can be collected for testing after patients avoid urinating for at least two hours 1
- Remove purulent discharge with a cotton-wool swab before urine collection if present 1
Management Approaches for Common Urethral Meatal Conditions
Meatal Stenosis
- Surgical correction through meatotomy or meatoplasty is indicated for symptomatic cases 4
- For meatal stenosis due to thin ventral web, wedge urethral meatotomy (V-shaped excision) shows good outcomes 4
- Post-procedure care includes meatal edge separation three times daily for ten days with topical antibiotic application 4
Urethral Trauma Management
- Establish prompt urinary drainage in patients with pelvic fracture associated urethral injury 1
- For penile fracture with concomitant urethral injury, surgical exploration and repair is indicated 1
- Avoid repeated attempts at placing a urethral catheter in trauma cases as this may increase injury extent 1
Urethral Caruncle
- Typically found in postmenopausal women, these benign outgrowths at the urethral meatus may require surgical excision if symptomatic 3
- Simple excision is the most common surgical approach 3
Special Considerations
Pediatric Patients
- In children with suspected meatal stenosis, uroflowmetry is valuable for diagnosis 5
- For newborn examination, use a thin swab on an aluminum shaft 1
- Surgical treatment is curative for congenital meatal urethral stenosis 5
Female-Specific Considerations
- Urethral meatus may be difficult to access due to morphological abnormalities (buried meatus) or congenital variations (urethral hypospadias) 2
- Difficulties in locating the female urethral meatus may be due to obesity, adductor muscle spasticity, vulvovaginal atrophy, or pelvic organ prolapse 2
Pitfalls to Avoid
- Never perform blind basketing (stone extraction without endoscopic visualization) as this risks urethral injury 1
- Avoid blind catheterization in suspected urethral trauma cases 1
- Do not rely solely on clinical diagnosis for genital lesions as laboratory confirmation should always be sought 1
- Avoid fluoroscopic imaging of stones alone without direct urethroscopic vision during procedures 1