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Last updated: October 13, 2025View editorial policy

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Differential Diagnosis for Red Face Rash

  • Single most likely diagnosis
    • Rosacea: This is a common condition characterized by a red, flushed face, often accompanied by small, pus-filled bumps. It's more common in fair-skinned individuals and can be triggered by various factors including sun exposure, stress, and certain foods.
  • Other Likely diagnoses
    • Acne: Especially inflammatory acne, can cause redness and rash on the face, particularly in adolescents and young adults.
    • Contact Dermatitis: An allergic reaction or irritation from substances like makeup, skincare products, or hair dye can lead to a red, itchy rash on the face.
    • Eczema (Atopic Dermatitis): This condition can cause dry, itchy, and red skin, and while it's more common on other parts of the body, it can also occur on the face.
    • Sunburn: Prolonged exposure to the sun without adequate protection can cause a red, painful rash on the face.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Lupus: Systemic lupus erythematosus can cause a characteristic "butterfly" rash across the cheeks and nose, and missing this diagnosis could lead to serious complications.
    • Cellulitis: A bacterial infection of the skin that can cause redness, swelling, and warmth, typically on one side of the face. It requires prompt antibiotic treatment.
    • Erythema Multiforme: A skin condition characterized by target lesions, which can be triggered by infections or medications. It can be a sign of a more serious condition.
  • Rare diagnoses
    • Sarcoidosis: A condition that can cause small, raised bumps on the face, which can be accompanied by redness.
    • Carcinoid Syndrome: In rare cases, this condition can cause flushing of the face, among other symptoms.
    • Dermatomyositis: An inflammatory disease that can cause a distinctive red rash on the face, particularly around the eyes, as well as muscle weakness.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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