Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 14, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Leg and Foot Pain in Teenagers

Single Most Likely Diagnosis

  • Overuse injuries or shin splints: This is a common condition in teenagers, especially those involved in sports or physical activities, due to repetitive stress on the muscles and bones of the lower leg.
  • Growing pains: Although more common in younger children, some teenagers may still experience growing pains, which are recurrent pains in the legs, often at night, associated with growth spurts.

Other Likely Diagnoses

  • Muscle strains: Teenagers, especially athletes, are prone to muscle strains due to sudden stops, quick changes of direction, or direct blows to the muscle.
  • Ankle sprains: Common in teenagers due to sports injuries or simple twisting of the ankle.
  • Plantar fasciitis: Inflammation of the plantar fascia can cause pain in the heel and bottom of the foot, common in individuals who are overweight, have flat feet, or engage in activities that strain the heel.
  • Stress fractures: Small cracks in a bone, often caused by overuse and repetitive stress, common in athletes.

Do Not Miss Diagnoses

  • Osteosarcoma or other bone cancers: Although rare, bone cancers can present with leg or foot pain and must be considered to ensure early diagnosis and treatment.
  • Deep vein thrombosis (DVT): Can occur in teenagers, especially after long periods of immobility, and requires immediate medical attention due to the risk of pulmonary embolism.
  • Compartment syndrome: A condition where pressure within the muscles builds to dangerous levels, cutting off blood flow and potentially leading to permanent damage if not treated promptly.
  • Infections (e.g., osteomyelitis, septic arthritis): Bacterial infections of the bone or joint can cause severe pain and require urgent antibiotic treatment.

Rare Diagnoses

  • Ehlers-Danlos syndrome: A group of disorders that affect connective tissues supporting the skin, bones, blood vessels, and many other organs and tissues, which can lead to joint hypermobility and pain.
  • Marfan syndrome: A disorder that affects the connective tissue in many parts of the body, which can lead to musculoskeletal symptoms including joint pain.
  • Complex regional pain syndrome (CRPS): A chronic pain condition characterized by severe, burning pain at the site of an injury, which can be out of proportion to the severity of the initial injury.
  • Peripheral neuropathy: Damage to the peripheral nerves can cause pain, numbness, or weakness in the legs and feet, which is rare in teenagers but can be associated with certain conditions like diabetes or vitamin deficiencies.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.