Management of Post Sleeve Gastrectomy Stenosis
Endoscopic pneumatic balloon dilation is the first-line treatment for post sleeve gastrectomy stenosis, with a success rate of approximately 76% in providing long-term symptom relief. 1, 2
Types of Stenosis and Initial Assessment
- Post sleeve gastrectomy stenosis occurs in approximately 0.7-5% of cases, commonly located at the incisura angularis or in the proximal stomach 1, 3
- Stenosis can be classified as:
- Organic: visible luminal narrowing
- Functional: deformation without obvious narrowing
- Combined: features of both 3
- Endoscopic assessment should be the first step in stable patients presenting with gastrointestinal symptoms suggestive of stenosis 1
Endoscopic Management Algorithm
First-Line Approach: Balloon Dilation
- Pneumatic balloon dilation is the preferred first-line treatment for most post-sleeve gastrectomy stenoses 1
- Technical specifications:
- Use large pneumatic balloons (30-40 mm diameter, 8-10 cm long)
- Position with endoscope side-by-side to the balloon
- Inflate to 20 psi for 1-3 minutes
- Use carbon dioxide for insufflation during the procedure 1
- Fluoroscopy is recommended (though not mandatory) to ensure proper balloon placement and avoid crossing the pylorus 1
- After dilation, inspect for tears; if tears involve the muscularis propria, consider endoscopic suturing to close the defect 1
- Dilations can begin as early as 2 weeks after surgery 1
- Serial dilations may be required, typically spaced 2-4 weeks apart 1, 4
For Refractory Stenosis
- If stenosis persists after 2-3 dilations to a maximum diameter of 35 mm, consider placement of a fully covered self-expanding metal stent (FCSEMS) 1
- The stent should:
- The purpose of the stent is to improve pressure and flow dynamics 1
Surgical Options for Failed Endoscopic Management
- If endoscopic management fails after multiple attempts, conversion to Roux-en-Y gastric bypass should be considered 1, 4
- Approximately 17% of patients may ultimately require salvage surgery 2
Efficacy and Safety Considerations
- Overall success rate of endoscopic balloon dilation is approximately 76% (95% CI, 67%-86%) 2
- Success rates vary by location:
- Proximal stenosis: 90% (95% CI, 63%-98%)
- Distal stenosis: 70% (95% CI, 47%-86%) 2
- Perforation is a rare but serious complication, occurring in approximately 0.9-1.5% of cases 5, 2
- If perforation is suspected, inject contrast to assess for extravasation 1
- Consider performing the procedure in an operating room with a surgeon present (preferably the original surgeon) for critically ill patients or when the endoscopist has limited experience 1
Special Considerations
- Downstream stenosis may contribute to staple-line leaks by increasing intraluminal pressure 1
- Patients with stenosis often have higher depression and anxiety scores and lower quality of life, requiring a multidisciplinary approach 1, 6
- For patients with severe stenosis or helical stenosis that fails to respond to endoscopic therapy, revision to Roux-en-Y gastric bypass may be necessary 4
- Mild weight regain (approximately 3 kg or 4.2% of total body weight) may occur following successful endoscopic dilation 5
By following this algorithmic approach to managing post sleeve gastrectomy stenosis, clinicians can achieve high success rates while minimizing the need for more invasive surgical interventions.