From the Research
For a child weighing 35 kg at 11 years old, the recommended dose of diclofenac syrup would be 1 mg/kg/dose, which translates to approximately 35 mg per dose, given three times daily. This recommendation is based on the most recent and highest quality study available, which suggests that diclofenac is an effective analgesic for acute pain in children, with a good safety profile 1. The study recommends a dose of 1 mg/kg for oral diclofenac in children aged 1-12 years, which yields a similar area under the concentration-time curve (AUC) to a 50-mg dispersible tablet in adults.
Key Considerations
- Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that works by reducing inflammation and pain.
- The medication should only be given under medical supervision, as it carries risks including gastrointestinal effects.
- The combination of diclofenac with other medications, such as acetaminophen, can be used to achieve similar analgesia with lower doses of both drugs 2.
- The duration of treatment should be limited to the shortest period necessary to control symptoms, typically 3-5 days unless otherwise directed by a healthcare provider.
- It is essential to administer the medication with food to minimize stomach irritation and ensure the child stays well-hydrated while taking the medication.
Dosage and Administration
- The recommended dose of diclofenac syrup is 1 mg/kg/dose, given three times daily.
- For an 11-year-old child weighing 35 kg, the dose would be approximately 35 mg per dose.
- The medication should be administered orally, with food, to minimize stomach irritation.
Safety and Efficacy
- Diclofenac has been shown to be an effective analgesic for acute pain in children, with a good safety profile 3.
- The medication carries risks, including gastrointestinal effects, and should be used with caution.
- The combination of diclofenac with other medications, such as acetaminophen, can be used to achieve similar analgesia with lower doses of both drugs, reducing the risk of adverse effects.