What is the recommended treatment for partial thickness burns?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 14, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Treatment for Partial Thickness Burns

The recommended first-line treatment for partial thickness burns is immediate cooling with clean running water for 5-20 minutes, followed by application of a petrolatum-based antibiotic ointment and covering with a clean, non-adherent dressing. 1, 2, 3

Initial Management

  • Immediately cool the burn with clean running water for 5-20 minutes to limit tissue damage and reduce pain 1, 2, 3
  • Remove any jewelry from the affected area before swelling occurs to prevent constriction and vascular ischemia 2, 3
  • Monitor children closely for signs of hypothermia during cooling, especially with larger burns 2
  • Administer over-the-counter pain medications like acetaminophen or NSAIDs for pain management 2, 3

Wound Care After Cooling

  • Gently cleanse the burn with tap water or isotonic saline 4
  • Apply a thin layer of petrolatum-based antibiotic ointment (such as bacitracin, Polysporin, or triple-antibiotic ointment) directly to the burn 4, 5
  • Cover with a clean, non-adherent dressing such as:
    • Xeroform (petrolatum-impregnated gauze) 4
    • Mepitel (silicone-coated dressing) 4
    • Allevyn (polyurethane foam dressing) 4, 6
  • Clean gauze can be used as a secondary dressing over the non-adherent primary dressing 4

Evidence for Treatment Options

  • Petrolatum gel alone has shown comparable or better results than silver sulfadiazine in terms of healing time (6.2 days vs 7.8 days) and was associated with less painful dressing changes 5
  • Silver-containing foam dressings have shown no significant difference in wound healing compared to silver sulfadiazine with gauze, but may offer reduced pain during early treatment and potentially decreased infection rates 6
  • Hydrocolloid dressings with silver sulfadiazine (Urgotul SSD) have demonstrated shorter healing times (10 days vs 12 days) and significantly lower pain scores compared to traditional silver sulfadiazine dressings 7
  • Bioengineered skin substitutes have shown significant improvements in healing rate, decreased wound care time, and reduced pain compared to topical antibiotics for facial burns 8

Important Considerations and Pitfalls

  • Avoid applying ice directly to burns as this can cause further tissue damage 4, 2
  • Do not apply butter, oil, or other home remedies to burns 4, 2
  • Do not break blisters, as this increases infection risk 2
  • Be aware that silver sulfadiazine may cause transient leukopenia, skin necrosis, erythema multiforme, and delayed eschar separation 9
  • Mafenide acetate can cause metabolic acidosis due to carbonic anhydrase inhibition and should be used with caution in patients with renal dysfunction 10

When to Seek Medical Attention

  • Burns involving the face, hands, feet, or genitalia 4, 2, 3
  • Burns covering more than 10% body surface area (5% in children) 4, 2, 3
  • Burns that show signs of infection or are very painful 4, 2
  • Burns with signs of inhalation injury (soot around nose/mouth, difficulty breathing) 2, 3
  • All full-thickness (third-degree) burns 2

The American Burn Association recommends that patients with partial-thickness burns involving more than 10% body surface area be treated in a specialized burn center 3.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

First Aid Treatment for Burns from Hot Metal Contact

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Burn Treatment and Management for Partial-Thickness Burns

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Management of First-Degree Burns

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

A systematic review of foam dressings for partial thickness burns.

The American journal of emergency medicine, 2019

Research

Benefit of hydrocolloid SSD dressing in the outpatient management of partial thickness burns.

Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2009

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.