Bulletproof Brain Octane C8 MCT Oil: Effects and Recommended Usage
Bulletproof Brain Octane C8 MCT oil has potential cognitive benefits in specific populations, but current evidence is insufficient to recommend its general use for cognitive enhancement in healthy individuals. 1
What is MCT Oil?
- Medium-chain triglycerides (MCTs) are metabolized to ketone bodies that can serve as an alternative energy source for neurons 1
- C8 MCT oil (caprylic acid) is a specific type of MCT that contains 8-carbon fatty acid chains 2
- MCT oils are derived from sources like coconut oil and provide medium chain fatty acids, which are metabolized differently than long-chain fatty acids 1
Potential Benefits
- MCTs may improve cognition in patients with mild to moderate dementia, particularly in APO-E4 negative subjects 1
- In a 6-month study of Alzheimer's disease patients, 80% of subjects taking MCT oil (average 1.8 tablespoons/day) remained stable or improved in cognitive function 3
- MCT supplementation increased serum ketone bodies and improved memory in a small pilot study of patients with mild cognitive impairment 4
- In healthy young adults, MCT supplementation (C8:C10 ratio of 30:70) enhanced performance in cognitive tasks including Trail Making and Digit Span after 2-3 weeks of supplementation 5
- MCT oil supplementation has shown potential in reducing seizure frequency in some epilepsy patients as an alternative to the standard ketogenic diet 6
Dosing Considerations
- In studies showing cognitive benefits, dosages ranged from 25-42g per day (approximately 1.8-3 tablespoons daily) 3, 4
- In healthy young adults, cognitive benefits were observed with 12g of MCT per day, with minimal additional benefit at 18g per day, suggesting a possible dose-response threshold 5
- For seizure reduction, one case report noted benefits at a dose of four tablespoons twice daily 6
Side Effects and Tolerability
- Common adverse effects include gastrointestinal problems such as diarrhea, dyspepsia, and flatulence 1
- Higher doses may lead to significant diarrhea and flatulence, limiting tolerability 6
- MCT oil adds calories to the diet (approximately 130 calories per tablespoon) 3
Important Caveats
- Despite some promising results, current evidence is insufficient to recommend MCT oil for general cognitive enhancement 1
- Clinical guidelines specifically state: "We do not recommend any other nutritional product for persons with dementia to correct cognitive impairment or prevent further cognitive decline" (Grade of evidence: very low) 1
- Most studies showing benefits were small, short-term, or had methodological limitations 3, 4
- Benefits may be more pronounced in specific populations (elderly, cognitive impairment) rather than healthy individuals 1
- The effects may differ between different types of MCTs (C8 vs. C10) 2
Practical Recommendations
- Start with a low dose (1 tablespoon daily) and gradually increase to minimize gastrointestinal side effects 6
- Can be added to coffee, smoothies, or other foods that don't require heating
- Monitor for gastrointestinal tolerance and adjust dosage accordingly 6
- For those seeking cognitive benefits, consistency in daily usage for at least 2-3 weeks may be necessary before noticing effects 5
- Those with medical conditions should consult healthcare providers before starting supplementation, particularly individuals with liver or pancreatic disorders 1
While some evidence suggests potential benefits of MCT oil for cognitive function in specific populations, larger and longer-term studies are needed to fully establish its efficacy and optimal dosing regimens 1, 3.