What is the cause of acute left wrist swelling and tenderness?

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Last updated: March 24, 2025View editorial policy

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Differential Diagnosis for Acute Left Wrist Swelling and Tenderness

  • Single Most Likely Diagnosis
    • Traumatic injury (e.g., sprain or fracture): This is the most likely diagnosis due to the acute onset of swelling and tenderness, which are common symptoms of traumatic injuries to the wrist.
  • Other Likely Diagnoses
    • Osteoarthritis: Although less likely to cause acute symptoms, osteoarthritis can lead to wrist swelling and tenderness, especially if there's a recent increase in activity or a flare-up of the condition.
    • Rheumatoid arthritis: This chronic autoimmune disorder can cause wrist swelling, tenderness, and stiffness, and although it's not typically acute, a flare-up could present with these symptoms.
    • Gout: An acute gout attack can cause sudden onset of swelling, redness, and tenderness in the wrist, although it's more commonly associated with the big toe.
  • Do Not Miss Diagnoses
    • Septic arthritis: Although less common, septic arthritis is a medical emergency that requires prompt treatment. It can cause acute wrist swelling, tenderness, and fever, and missing this diagnosis could lead to serious complications.
    • Compartment syndrome: This is a rare but potentially devastating condition that can occur after a traumatic injury, causing increased pressure within the wrist compartments, which can lead to nerve and muscle damage if not promptly treated.
  • Rare Diagnoses
    • Scaphoid fracture with avascular necrosis: While not the most common fracture, a scaphoid fracture can occur, and if not properly treated, can lead to avascular necrosis, which is a rare but serious complication.
    • Kienbock's disease (avascular necrosis of the lunate bone): This rare condition can cause wrist pain and swelling due to the loss of blood supply to the lunate bone.
    • Ganglion cyst: Although typically not acute, a ganglion cyst can cause wrist swelling and tenderness, especially if it becomes inflamed or ruptures.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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