Radiographic Features of Psoriatic Arthritis on X-ray
The characteristic radiographic features of psoriatic arthritis (PsA) on X-ray include erosions with accompanying bone proliferation, asymmetric joint involvement with predilection for distal interphalangeal joints, pencil-in-cup deformities, periostitis, and ankylosis. 1
Key Radiographic Features to Look For
Distribution Pattern
- Most frequently involved joints are hands and wrists, followed by feet, ankles, knees, and shoulders 1
- Asymmetric pattern of joint involvement is characteristic of PsA 1
- Distal interphalangeal (DIP) joint involvement is a distinctive feature compared to rheumatoid arthritis 1
Destructive Changes
- Erosions typically start at joint margins and progress toward the center 1
- Erosions may become extensive, giving the appearance of widened rather than narrowed joint spaces 1
- Marked osteolysis in severely destroyed joints can lead to complete destruction of phalanges 1
Proliferative Changes
- Erosions with accompanying increased bone production (a distinguishing feature from rheumatoid arthritis) 1
- Juxta-articular new bone formation (included in CASPAR diagnostic criteria) 1
- Periostitis affecting both periarticular areas and bone shafts 2
Characteristic Deformities
- "Pencil-in-cup" phenomenon: blunt osseous surface on proximal bone protruding into expanded surface of distal bone 1, 3
- This occurs due to widespread erosive changes combined with bone proliferation 1
- Arthritis mutilans (severe form with osteolysis) may be observed 1
Other Features
- Joint space narrowing may be present but is less prominent than in rheumatoid arthritis 1
- Ankylosis (fusion) of joints may occur in advanced disease 1, 2
- Spur formation at sites of enthesitis 2
Scoring Methods for Radiographic Assessment
- Several scoring methods have been developed for assessing structural damage in PsA 1
- The Sharp-van der Heijde modified scoring method evaluates erosions, joint space narrowing, subluxation, ankylosis, gross osteolysis, and "pencil-in-cup" phenomena 1
- Unlike rheumatoid arthritis scoring, PsA scoring includes evaluation of DIP joints 1
Clinical Correlation
- Radiographic findings may not correlate with the severity of skin disease 1
- Structural damage on radiographs is an important outcome measure in judging treatment efficacy 1
- Early inflammatory changes affecting soft tissue and bone marrow may not be detectable on plain radiographs 4
Advanced Imaging Considerations
- When X-rays are negative but PsA is still suspected, more sensitive imaging modalities like MRI or ultrasound may be needed 1
- MRI can detect early inflammatory changes including synovitis, enthesitis, and bone marrow edema 1
- Ultrasound can identify synovial hypertrophy and increased blood flow on color Doppler imaging 1
Remember that radiographic features typically occur in advanced disease, and early PsA may not show distinctive changes on X-ray 4. The combination of both destructive and proliferative changes in the same joint is highly characteristic of PsA and helps differentiate it from other inflammatory arthritides 5.