What to do if a central line is placed in the brachiocephalic vein?

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Last updated: October 15, 2025View editorial policy

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Management of Central Line in the Brachiocephalic Vein

A central line placed in the brachiocephalic vein can be safely maintained and used for intended purposes as this is a viable and acceptable central venous access site. 1, 2

Assessment of Catheter Position

  • Confirm proper tip position via chest X-ray - the tip should be in the lower third of the superior vena cava, at the atrio-caval junction, or in the upper portion of the right atrium 1
  • Check for signs of proper function including:
    • Ability to aspirate blood from all lumens 1
    • Normal pressure waveform 1
    • Absence of pain on injection 1
  • Look for signs of malposition such as:
    • Difficulty aspirating blood from one or more lumens 1
    • Abnormal pressure waveform 1
    • Pain on injection 1
    • Arterial pattern blood gas on sampling 1

Management Options

If Properly Positioned and Functioning:

  • Continue using the catheter for its intended purpose 1
  • Maintain proper catheter care including:
    • Use of 2% chlorhexidine as skin antiseptic for dressing changes 1
    • Appropriate dressing of the exit site 1
    • Disinfection of hubs, stopcocks and needle-free connectors 1
    • Regular change of administration sets 1

If Malpositioned but Still Within Venous System:

  • Consider the following options:
    1. Use the device if it is safe to do so and functioning properly 1
    2. Manipulate the position under X-ray guidance 1
    3. Replace the catheter using fluoroscopic guidance or other imaging as required 1

Evidence Supporting Brachiocephalic Vein Access

  • The brachiocephalic vein is a viable alternative to traditional central venous access sites 1, 3
  • Studies show comparable or lower complication rates compared to internal jugular vein access:
    • Similar overall failure rates (3.5% vs 3.4%) 3
    • Lower procedural difficulty compared to internal jugular approach 3
    • Lower risk of catheter-related bloodstream infections and thrombosis in pediatric populations 4, 5

Advantages of Brachiocephalic Vein Access

  • The supraclavicular approach to the brachiocephalic vein offers excellent in-plane needle visualization not interrupted by bony structures 2
  • Allows visualization of the distal end of the subclavian and brachiocephalic veins 2
  • May be associated with lower risk of catheter-related complications compared to other sites 4, 6
  • Well-tolerated in both pediatric and adult populations 7, 3

Potential Complications and Monitoring

  • Monitor for common complications of central venous access:
    • Infection at insertion site or catheter-related bloodstream infection 1
    • Venous thrombosis 1
    • Catheter dislodgement 6
    • Catheter malfunction 6

When to Remove or Replace

  • Remove the catheter when:
    • It is no longer required 1
    • It is causing problems (infection, thrombosis, malfunction) 1
    • For removal technique:
      • Position patient flat with exit site below the heart to reduce risk of air embolism 1
      • Apply firm digital pressure for at least 5 minutes followed by an occlusive dressing 1
      • Consider a skin stitch if persistent bleeding occurs 1

Key Pitfalls to Avoid

  • Failing to confirm proper tip position before use 1
  • Ignoring signs of catheter malfunction or malposition 1
  • Inadequate sterile technique during catheter maintenance 1
  • Unnecessary removal of a properly functioning catheter 1, 2

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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