What are the latest evidence-based practices in emergency medicine?

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Last updated: October 15, 2025View editorial policy

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Latest Evidence-Based Practices in Emergency Medicine

Emergency medicine should implement evidence-based protocols that focus on patient-centered outcomes, with particular emphasis on reducing morbidity and mortality through standardized approaches to care.

Systems-Based Approaches to Patient Safety

  • High-reliability organizations (HROs) operate in high-risk environments while maintaining low rates of injury by acknowledging that mishaps can occur at any time and implementing systems to minimize risk 1
  • Standardization of processes based on evidence rather than individual preference is a key component of the systems-based approach to emergency care 1
  • Hand-washing remains one of the simplest yet most effective evidence-based practices for infection control in emergency settings 1

Stroke Management in Emergency Settings

  • For acute ischemic stroke with large vessel occlusion, mechanical thrombectomy (with or without intravenous thrombolysis) is now standard of care, with potential to prevent severe disability and mortality 1
  • The time window for mechanical thrombectomy has been extended based on imaging criteria, allowing more patients to benefit from this intervention 1
  • Implementation of stroke protocols requires addressing barriers such as knowledge gaps, environmental constraints, and resource limitations 1
  • Behavior change techniques focused on "past success" and "information about health consequences" are most effective in improving adherence to stroke protocols 1

Cardiopulmonary Resuscitation and Cardiac Care

  • The American Heart Association has transitioned from periodic reviews to continuous evidence evaluation for resuscitation guidelines, allowing for more immediate implementation of new evidence 1
  • Emergency departments have shown improvement in STEMI care processes, with decreased door-to-catheterization times (from 62 to 37 minutes) and increased use of antithrombotic and antiplatelet agents 2
  • High-quality CPR remains the cornerstone of resuscitation efforts, with emphasis on minimizing interruptions and ensuring adequate depth and rate 1

First Aid and Initial Management

  • For life-threatening bleeding, evidence supports the use of tourniquets, hemostatic dressings, direct pressure, or pressure devices 1
  • Glucose administration methods for hyperthermia, cooling techniques for hyperthermia, and temporary storage of avulsed teeth have been evaluated with evidence-based recommendations 1
  • Early recognition of acute stroke and appropriate first aid measures are critical for improving outcomes 1

Antimicrobial Stewardship in Emergency Departments

  • Implementation of antimicrobial stewardship in emergency departments requires consideration of specific barriers including high staff turnover, rapid patient turnover, and the need for quick decisions 1
  • Successful implementation requires a diagnostic analysis to identify facilitators and barriers specific to each prescribing practice 1
  • Seven domains of determinants affect implementation: guideline factors, individual health professional factors, patient factors, professional interactions, incentives and resources, capacity for organizational change, and social/political/legal factors 1

Antidote Stocking and Management

  • Inadequate stocking of antidotes has been repeatedly documented in many countries, including the United States and Canada 1
  • Expert consensus recommends specific antidotes that should be stocked in hospitals providing emergency care, based on systematic review of the literature 1
  • Barriers to adequate antidote stocking include limited awareness, infrequent use, supply interruptions, and allocation of limited hospital pharmacy resources 1

Community-Acquired Pneumonia Management

  • Risk stratification tools help determine whether patients with community-acquired pneumonia can be treated as outpatients or require admission 1
  • Clinical judgment should be complemented by validated risk stratification tools to guide disposition decisions 1
  • Patients from nursing homes with pneumonia should be included in community-acquired pneumonia protocols 1

Medication Safety in Emergency Settings

  • Careful monitoring of cardiovascular and respiratory vital signs is essential when administering local anesthetics like lidocaine 3
  • Early warning signs of central nervous system toxicity include restlessness, anxiety, tinnitus, dizziness, blurred vision, tremors, depression, and drowsiness 3
  • Management of local anesthetic emergencies requires immediate attention to airway maintenance and assisted ventilation with oxygen 3

Implementation Challenges in Emergency Medicine

  • Emergency medicine faces unique challenges in implementing evidence-based medicine due to multiple, synchronous, and interdependent management questions 4
  • The episodic nature of emergency care, high staff turnover, and overcrowding create barriers to implementation of evidence-based practices 1
  • More than 50% of emergency procedures lack robust evidence, highlighting the need for more high-quality research specific to emergency settings 5

Palliative Care in Emergency Settings

  • Emergency department-based palliative care interventions have been shown to reduce hospital length of stay in six out of eight studies 6
  • Evidence for the impact of ED-based palliative care interventions on other outcomes such as return visits and mortality remains less robust 6
  • More high-quality comparative studies are needed to better understand the overall impact of ED-based palliative care interventions 6

Practical Implementation Strategies

  • Evidence-based practices should be implemented using a systematic, step-by-step approach that considers local barriers and facilitators 1
  • Successful implementation requires understanding the specific factors that influence success or failure in a particular hospital or ward 1
  • Emergency departments should develop methods for incorporating evidence into practice in anticipation of clinical situations, given the challenges of "real-time" application 4

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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