Differential Diagnosis for Right Sided Facial Pressure and Discomfort when Closing Eye

• Single Most Likely Diagnosis
  • Dry Eye Syndrome: This condition is characterized by inflammation of the ocular surface and lacrimal gland, which can cause discomfort, especially when closing the eye. The right-sided facial pressure could be related to referred pain from the eye.
• Other Likely Diagnoses
  • Blepharitis: Inflammation of the eyelids can cause discomfort, itching, and pressure around the eyes, which could be exacerbated by closing the eye.
  • Sinusitis: Given the location of the sinuses near the eyes, sinus infections can cause facial pressure, especially on one side, and discomfort that might worsen with certain movements like closing the eye.
  • Temporomandibular Joint (TMJ) Disorder: While primarily associated with jaw pain, TMJ disorders can also cause facial pain and pressure, including around the eyes, due to the complex anatomy of the facial nerves.
• Do Not Miss Diagnoses
  • Acute Angle-Closure Glaucoma: A medical emergency that can cause severe eye pain, blurred vision, and facial pain, especially around the eye. It's crucial to rule out this condition due to its potential for permanent vision loss if not promptly treated.
  • Orbital Cellulitis: An infection of the tissues surrounding the eye, which can cause pain, swelling, and pressure around the eye. It requires immediate medical attention to prevent serious complications.
• Rare Diagnoses
  • Trigeminal Neuralgia: A chronic pain condition that affects the trigeminal nerve, which can cause intense pain in parts of the face, including the area around the eye. It's less common but should be considered if other diagnoses are ruled out.
  • Raeder's Syndrome: A rare condition characterized by a combination of symptoms including facial pain, ptosis (drooping eyelid), and decreased sweating on the same side of the face. It's a rare diagnosis but could explain the combination of facial pressure and discomfort when closing the eye.