From the Guidelines
The brand name for sertraline is Zoloft. Sertraline is a selective serotonin reuptake inhibitor (SSRI) antidepressant medication commonly prescribed to treat depression, anxiety disorders, post-traumatic stress disorder, obsessive-compulsive disorder, panic disorder, and premenstrual dysphoric disorder. While Zoloft is the original and most recognized brand name, sertraline is also available as a generic medication which is chemically identical but typically less expensive. The medication works by increasing serotonin levels in the brain, a neurotransmitter that helps maintain mental balance.
Key Points
- Sertraline typically comes in tablet form in various strengths (25mg, 50mg, 100mg) and as an oral solution (20mg/mL) 1.
- Treatment usually begins with a lower dose that may be gradually increased by a healthcare provider based on the patient's response and tolerance to the medication.
- According to the guidelines, sertraline has less effect on metabolism of other medications compared to other SSRIs 1.
- The recommended initial dosage of sertraline is 25 to 50 mg per day, with a maximum dosage of 200 mg per day (morning or evening) 1.
- Sertraline is well tolerated, with typical side effects including sweating, tremors, nervousness, insomnia or somnolence, dizziness, and various gastrointestinal and sexual disturbances 1.
From the Research
Brand Name of Sertraline
The brand name of sertraline, a Selective Serotonin Reuptake Inhibitor (SSRI), is:
Key Points
- Sertraline is used to treat various psychiatric disorders, including depression, anxiety disorders, and obsessive-compulsive disorder 2, 5, 6, 4
- It has a favorable safety profile, with low risk of lethality in overdose and no dependence potential 2, 5, 4
- Sertraline is considered a first-line treatment for anxiety and depressive disorders due to its efficacy, tolerability, and lack of pharmacokinetic interactions 2, 5, 4