Treatment of Bell's Palsy
Oral corticosteroids should be prescribed within 72 hours of symptom onset as the first-line treatment for Bell's palsy in patients 16 years and older. 1, 2, 3
First-Line Treatment
- Recommended corticosteroid regimens include prednisolone 50 mg daily for 10 days, or prednisone 60 mg daily for 5 days followed by a 5-day taper 1, 2, 3
- Strong evidence supports corticosteroid use, with studies showing 83% recovery at 3 months with prednisolone versus 63.6% with placebo, and 94.4% recovery at 9 months with prednisolone versus 81.6% with placebo 1, 2, 4
- Treatment should be initiated within 72 hours of symptom onset for maximum effectiveness 2, 3
Eye Protection
- Eye protection is essential for all Bell's palsy patients with impaired eye closure to prevent corneal damage 2, 5
- Protective measures include lubricating ophthalmic drops, ophthalmic ointments, eye patching or taping, and sunglasses for outdoor protection 2
Antiviral Therapy
- Antiviral therapy alone should NOT be prescribed for Bell's palsy as it is ineffective 2, 3, 6
- Combination therapy with oral antivirals and corticosteroids may be considered as an option within 72 hours of symptom onset 2, 3
- Some evidence suggests combination therapy may reduce rates of synkinesis (involuntary co-contraction of facial muscles) 6
- When used, recommended antivirals include valacyclovir (1 g three times daily for 7 days) or acyclovir (400 mg five times daily for 10 days) 6
Special Populations
Children
- Children with Bell's palsy have a better prognosis than adults, with higher rates of spontaneous recovery 2, 6
- Evidence for corticosteroid use in children is less conclusive 2, 3
Pregnant Women
- Pregnant women should receive oral corticosteroids within 72 hours of symptom onset, with careful individualized assessment of benefits and risks 2
- Spontaneous recovery rates in pregnant women can reach up to 90% 6
Follow-up and Monitoring
- Patients should be reassessed or referred to a facial nerve specialist if they have: 2, 3, 5
- New or worsening neurologic findings at any point
- Ocular symptoms developing at any point
- Incomplete facial recovery 3 months after initial symptom onset
Diagnostic Testing
- Routine laboratory testing and diagnostic imaging are NOT recommended for typical Bell's palsy diagnosis 2
- MRI with and without contrast is the imaging test of choice when indicated, such as for atypical presentations or no sign of recovery after 3 months 1, 2
Recovery Timeline
- Most patients begin showing signs of recovery within 2-3 weeks of symptom onset 2
- Complete recovery typically occurs within 3-4 months for most patients 2
- Approximately 70% of patients with complete paralysis recover facial function completely within 6 months 2
- Patients with incomplete paralysis have higher recovery rates, up to 94% 2
Emerging Research
- Recent research suggests high-dose corticosteroids (≥80 mg) may be more effective than standard doses (40-60 mg), showing decreased non-recovery at 6 months follow-up 7
- Physical therapy may be beneficial for patients with more severe paralysis and developing synkinesis, though evidence for specific protocols is limited 5, 6
Common Pitfalls to Avoid
- Delaying treatment beyond 72 hours, which reduces effectiveness of therapy 2, 3
- Using antiviral therapy alone, which is ineffective 2, 3, 6
- Failing to provide adequate eye protection for patients with impaired eye closure 2, 5
- Neglecting to reassess patients with incomplete recovery after 3 months 2, 5