What is the recommended dosage of steroid for the treatment of Morton's neuroma?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: March 24, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

For the treatment of Morton's neuroma, the recommended dosage of steroid is 40 mg of triamcinolone acetonide, as it has been shown to provide statistically significantly better functional and pain outcomes compared to other treatments, such as hyaluronic acid injections, as demonstrated in a recent study 1. The injection is typically administered directly into the affected intermetatarsal space where the neuroma is located, usually between the third and fourth metatarsal heads. Some key points to consider when administering steroid injections for Morton's neuroma include:

  • Using a local anesthetic, such as 1% lidocaine or 0.5% bupivacaine, in combination with the steroid to minimize discomfort during the procedure
  • Performing the injection under ultrasound guidance to ensure accurate placement of the steroid, as this has been shown to lead to greater long-term improvement compared to blind injections 2
  • Administering a series of up to three injections spaced 4-6 weeks apart, as some patients may require multiple injections to achieve optimal relief
  • Advising patients to rest the foot for 24-48 hours after injection and monitor for potential side effects, such as temporary pain flare-up, skin discoloration, or fat pad atrophy with repeated injections
  • Considering alternative treatments, such as surgical excision, if symptoms do not improve after 2-3 injections, as suggested in a review of current concepts in the treatment of Morton's neuroma 3.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.