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Last updated: October 15, 2025View editorial policy

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Differential Diagnosis for Scalp Tender to Touch

Single Most Likely Diagnosis

  • Tension headache: This is often the most common cause of scalp tenderness, as the muscles in the scalp can become tense and painful due to stress or other factors.

Other Likely Diagnoses

  • Scalp dermatitis (eczema or psoriasis): Inflammatory conditions of the scalp can cause tenderness and discomfort.
  • Folliculitis: An infection of the hair follicles can lead to pain and tenderness in the affected area.
  • Shingles (herpes zoster): Before the rash appears, patients may experience pain or tenderness in the affected dermatome, which can include the scalp.

Do Not Miss Diagnoses

  • Meningitis: Although less common, meningitis is a serious and potentially life-threatening condition that can cause scalp tenderness, especially if accompanied by fever, stiff neck, and altered mental status.
  • Subarachnoid hemorrhage: A severe headache (often described as "the worst headache of my life") can be associated with scalp tenderness due to irritation of the meninges.
  • Temporal arteritis (giant cell arteritis): This condition can cause scalp tenderness, especially in older adults, and is associated with other symptoms like jaw claudication and visual disturbances.

Rare Diagnoses

  • Trichodynia: A rare condition characterized by pain in the scalp, often associated with hair loss.
  • Neuropathic pain syndromes: Certain conditions like trigeminal neuralgia can cause pain in the scalp, although this is less common.
  • Metastatic cancer: Rarely, cancer that has spread to the scalp can cause tenderness, although this would typically be accompanied by other symptoms like a palpable mass.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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