What is the best medicine for athlete's foot in the UK?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 15, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Best Medicine for Athlete's Foot in the UK

Topical terbinafine 1% cream applied twice daily for 1 week is the most effective first-line treatment for athlete's foot (tinea pedis). 1, 2

First-Line Treatment Options

  • Terbinafine 1% cream is superior to other topical antifungals, achieving higher cure rates with shorter treatment duration (1 week vs 4 weeks for other options) 1, 3
  • Terbinafine has demonstrated mycological cure rates of 93.5% at 4 weeks compared to 73.1% for clotrimazole when applied twice daily 3
  • Terbinafine is FDA-approved specifically for curing athlete's foot and relieves associated symptoms like itching, burning, cracking, and scaling 2

Alternative Topical Options

  • Ciclopirox olamine 0.77% cream/gel applied twice daily for 4 weeks is effective with approximately 85% cure rate two weeks after treatment completion 4, 1
  • Clotrimazole 1% cream applied twice daily for 4 weeks is less effective than terbinafine but is widely available over-the-counter 1, 3
  • Miconazole nitrate 2% powder can be used, particularly when moisture absorption is desired 5, 6

When to Consider Oral Therapy

  • For severe, extensive, or treatment-resistant cases, consider oral antifungal therapy 1, 7
  • Oral terbinafine 250 mg once daily for 1 week offers faster clinical resolution compared to topical treatments 4
  • Oral itraconazole 100 mg daily for 2 weeks is an alternative but may have slightly higher relapse rates than terbinafine 4, 1

Clinical Considerations

  • Tinea pedis presents in three main forms: interdigital (most common), hyperkeratotic (moccasin-type), and vesiculobullous (inflammatory) 7
  • The interdigital form may present as simple dermatophytosis or complex dermatophytosis with secondary bacterial infection 8
  • For complex cases with bacterial involvement, ciclopirox gel may be advantageous due to its combined antifungal, antibacterial, and anti-inflammatory properties 8

Prevention Measures

  • Apply foot powder after bathing to reduce recurrence rates 4, 1
  • Thoroughly dry between toes after showering 4, 1
  • Change socks daily and periodically clean athletic footwear 4, 1
  • To prevent spread to the groin area (tinea cruris), cover active foot lesions with socks before wearing underwear 4

Common Pitfalls to Avoid

  • Clinical diagnosis alone has low accuracy; consider KOH wet-mount examination of skin scrapings for confirmation 7
  • Untreated tinea pedis can spread to other body parts or other people and may develop secondary bacterial infections 7, 9
  • Discontinuing treatment prematurely can lead to recurrence; complete the full recommended course even if symptoms improve 7
  • Patients with risk factors such as diabetes, obesity, or immunocompromised status may require longer treatment courses or oral therapy 4

References

Guideline

Treatment of Tinea Pedis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Athlete's foot.

BMJ clinical evidence, 2009

Research

Tinea pedis: an updated review.

Drugs in context, 2023

Research

Getting rid of athlete's foot.

Drug and therapeutics bulletin, 2002

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.