What are the best treatments for gas in an 18-day-old infant?

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Last updated: October 16, 2025View editorial policy

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Managing Gas in an 18-Day-Old Infant

For an 18-day-old infant with gas, the most effective approach is to use non-pharmacological interventions such as proper feeding techniques, frequent burping, and maintaining an upright position after feeding. 1, 2

Non-Pharmacological Management Strategies

  • Feeding Techniques:

    • For breastfed infants, consider a 2-4 week maternal elimination diet that restricts milk and egg, as milk protein allergy can mimic or exacerbate gas symptoms 2
    • For formula-fed infants, consider switching to an extensively hydrolyzed protein or amino acid-based formula if symptoms persist 2
    • Reduce feeding volume while increasing feeding frequency to minimize gastric distension 2
  • Positioning and Handling:

    • Hold the infant upright for 10-20 minutes after feeding to allow for adequate burping before placing them down 1
    • Avoid placing the infant in car seats or other semi-upine positions immediately after feeding, as this can exacerbate reflux and gas 1
    • Maintain a completely upright position when the infant is awake 2
  • Burping Techniques:

    • Ensure proper and frequent burping during and after feedings 1, 2
    • Place the infant on your shoulder and gently pat or rub their back 1

Important Considerations

  • Gas in young infants is often related to normal physiologic gastroesophageal reflux (GER), which occurs in 70-85% of infants within the first 2 months of life 3
  • Most cases resolve without intervention by 1 year of age 3, 4
  • Parental reassurance and education are crucial components of management 3
  • Left side positioning after feeding has shown evidence in reducing reflux symptoms, but should only be used when the infant is being observed (not for sleep) 5

When to Consider Medical Evaluation

  • Seek medical attention if the infant shows:
    • Poor weight gain 2
    • Forceful or projectile vomiting 2, 4
    • Blood in stool or vomit 2
    • Excessive irritability that doesn't improve with the above measures 2, 3

Caution Regarding Medications

  • Medications such as simethicone (gas drops) have not shown proven efficacy for gas-related symptoms in infants 6
  • Acid-suppression medications (PPIs, H2 blockers) should be avoided unless specifically prescribed for diagnosed GERD, as they may increase the risk of pneumonia and gastroenteritis 1, 7, 2

Follow-up

  • If symptoms persist despite conservative measures for 2 weeks, consider evaluation for other causes or referral to pediatric gastroenterology 2
  • Monitor weight gain closely as it is a primary outcome measure for infants with feeding difficulties 2

Remember that gas is a normal physiological process in infants, and most cases can be managed effectively with proper feeding techniques and positioning without the need for medication 1, 2, 3.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Gastroesophageal Reflux Disease in Infants

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Gastrointestinal gas formation and infantile colic.

Pediatric clinics of North America, 1996

Guideline

Treatment for Gastroesophageal Reflux Disease (GERD) in Children

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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