Differential Diagnosis for Common Rash with Bisters
- Single Most Likely Diagnosis
- Herpes Zoster (Shingles): This is a common condition characterized by a painful rash with blisters, typically affecting one side of the body. The rash usually appears in a dermatomal distribution, which helps in diagnosing the condition.
- Other Likely Diagnoses
- Varicella (Chickenpox): A highly contagious illness that causes an itchy, blister-like rash, fever, and fatigue. It's more common in children but can occur in adults, especially those who haven't been vaccinated or previously infected.
- Contact Dermatitis: This condition can cause blisters and a rash due to an allergic reaction or irritation from substances like poison ivy, certain metals, or chemicals.
- Herpes Simplex: This viral infection can cause blisters and rashes, typically around the mouth (HSV-1) or genitals (HSV-2).
- Do Not Miss Diagnoses
- Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN): These are severe skin conditions usually triggered by medications or infections. They can cause widespread skin lesions, blisters, and can be life-threatening if not promptly treated.
- Pemphigus Vulgaris: An autoimmune disease that causes severe blistering of the skin and mucous membranes. It's rare but can be fatal if not treated.
- Rare Diagnoses
- Bullous Pemphigoid: An autoimmune disease that causes large blisters on the skin, more common in older adults.
- Epidermolysis Bullosa: A group of genetic conditions that result in fragile skin and blisters.
- Porphyria Cutanea Tarda: A disorder that can cause blistering of the skin when exposed to sunlight, due to a deficiency in an enzyme involved in the production of heme.