Treatment for Constipation Lasting 2 Days
For constipation lasting 2 days, initial treatment should include increased fluid intake, dietary fiber, physical activity, and if needed, a stimulant laxative such as bisacodyl 10-15 mg daily with a goal of one non-forced bowel movement every 1-2 days. 1
First-Line Interventions
- Increase fluid intake to enhance the effectiveness of fiber and promote softer stools 1, 2
- Increase dietary fiber if patient has adequate fluid intake and physical activity 1
- Exercise, if appropriate, as 30 minutes per day can help alleviate constipation symptoms 1, 2
- Ensure privacy and comfort during defecation attempts 1
- Proper positioning (using a small footstool to assist with gravity during defecation) 1
Medication Options (If Lifestyle Modifications Are Insufficient)
Step 1: Stimulant Laxatives
- Bisacodyl 10-15 mg daily to three times daily with a goal of one non-forced bowel movement every 1-2 days 1
- Senna (with or without docusate) 2-3 tablets daily 1
Step 2: Osmotic Laxatives (If Stimulants Are Insufficient)
- Polyethylene glycol (PEG) 17g in 8 ounces of water daily - generally produces a bowel movement in 1-3 days 1, 3
- Lactulose 30-60 mL twice to four times daily 1
- Magnesium hydroxide 30-60 mL daily to twice daily 1
- Magnesium citrate 8 oz daily 1
Step 3: For Persistent Constipation
- Glycerin suppository or bisacodyl suppository (one rectally daily to twice daily) 1
- Consider combination therapy with different classes of laxatives 1
Special Considerations
- Rule out impaction, especially if diarrhea accompanies constipation (overflow around impaction) 1
- Discontinue any non-essential constipating medications (antacids, anticholinergics, antidepressants, antispasmodics, phenothiazines, haloperidol, and certain antiemetics) 1
- For opioid-induced constipation that doesn't respond to standard laxatives, consider methylnaltrexone 0.15 mg/kg subcutaneously (no more than once daily) 1
- Avoid long-term use of magnesium-based laxatives in patients with renal impairment due to potential toxicity 1, 4
Common Pitfalls to Avoid
- Bulk-forming agents like psyllium should be started slowly and with adequate fluid intake to prevent bloating and flatulence 2, 5
- Docusate sodium alone is generally insufficient for established constipation and has inadequate experimental evidence supporting its use 1, 6
- Avoid liquid paraffin (mineral oil) due to risks of aspiration, anal seepage, and skin excoriation 1
- Don't ignore underlying causes of constipation such as hypercalcemia, hypokalemia, hypothyroidism, or diabetes mellitus 1
Remember that while most cases of constipation lasting only 2 days can be managed with lifestyle modifications and over-the-counter remedies, persistent symptoms warrant further evaluation to identify potential underlying causes 4, 7.