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Differential Diagnosis

  • Single most likely diagnosis
    • Pharyngeal diphtheria: The presence of a gray-dirty coating on the tonsils that is difficult to remove and bleeds upon removal is highly suggestive of a diphtheric membrane, which is characteristic of pharyngeal diphtheria. The acute onset of illness, high fever, and the epidemiological link to another case also support this diagnosis.
  • Other Likely diagnoses
    • Infectious mononucleosis: The symptoms of fever, sore throat, and enlarged lymph nodes could be consistent with infectious mononucleosis, especially in a young adult. However, the presence of a gray-dirty coating on the tonsils is not typical.
    • Tularemia oropharyngeal form: Although less common, tularemia can present with pharyngitis and a history of exposure to infected animals or contaminated water. The symptoms and signs could fit, but the epidemiological history provided does not strongly support this diagnosis.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Pharyngeal diphtheria (also listed as the most likely diagnosis due to its severity and the need for prompt treatment): It's crucial not to miss this diagnosis due to its potential for severe complications and high mortality if not treated promptly with antitoxin and antibiotics.
  • Rare diagnoses
    • Yersiniosis respiratory form: This is a rare cause of pharyngitis and would be less likely without specific exposure history (e.g., to contaminated food or water).
    • Tularemia oropharyngeal form (also listed under other likely diagnoses): While it's considered in the differential for its severity, it's relatively rare and would require specific exposure risks.
    • Chronic tonsillitis: The acute presentation and specific findings (e.g., the gray-dirty coating) make chronic tonsillitis an unlikely diagnosis for this acute illness.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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